{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Che S"],"funding":["HHS | NIH | National Institute of Environmental Health Sciences","DOD | Strategic Environmental Research and Development Program","NIEHS NIH HHS","DOD | Strategic Environmental Research and Development Program (SERDP)","HHS | NIH | National Institute of Environmental Health Sciences (NIEHS)"],"pagination":["e2400525121"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11295042"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["121(31)"],"pubmed_abstract":["Per- and polyfluoroalkyl substances (PFAS), particularly the perfluorinated ones, are recalcitrant to biodegradation. By integrating an enrichment culture of reductive defluorination with biocompatible electrodes for the electrochemical process, a deeper defluorination of a C<sub>6</sub>-perfluorinated unsaturated PFAS was achieved compared to the biological or electrochemical system alone. Two synergies in the bioelectrochemical system were identified: i) The in-series microbial-electrochemical defluorination and ii) the electrochemically enabled microbial defluorination of intermediates. These synergies at the material-microbe interfaces surpassed the limitation of microbial defluorination and further turned the biotransformation end products into less fluorinated products, which could b"],"journal":["Proceedings of the National Academy of Sciences of the United States of America"],"pubmed_title":["Synergistic material-microbe interface toward deeper anaerobic defluorination."],"pmcid":["PMC11295042"],"funding_grant_id":["ER20-1541","R01 ES032668","R01ES032668"],"pubmed_authors":["Rodrigues R","Che S","Men Y","Xie Y","Guan X","Liu C","Yu Y"],"additional_accession":[]},"is_claimable":false,"name":"Synergistic material-microbe interface toward deeper anaerobic defluorination.","description":"Per- and polyfluoroalkyl substances (PFAS), particularly the perfluorinated ones, are recalcitrant to biodegradation. By integrating an enrichment culture of reductive defluorination with biocompatible electrodes for the electrochemical process, a deeper defluorination of a C<sub>6</sub>-perfluorinated unsaturated PFAS was achieved compared to the biological or electrochemical system alone. Two synergies in the bioelectrochemical system were identified: i) The in-series microbial-electrochemical defluorination and ii) the electrochemically enabled microbial defluorination of intermediates. These synergies at the material-microbe interfaces surpassed the limitation of microbial defluorination and further turned the biotransformation end products into less fluorinated products, which could b","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jul","modification":"2025-04-03T23:36:43.421Z","creation":"2025-04-03T23:36:43.421Z"},"accession":"S-EPMC11295042","cross_references":{"pubmed":["39042683"],"doi":["10.1073/pnas.2400525121"]}}