biostudies-literatureShao RBeijing Hospitals Authority's Ascent PlanBeijing Hospitals Authority&apos;s Ascent PlanHigh-Level Public Health Technical Talent Building ProgramNational Natural Science Foundation of ChinaCapital’s Funds for Health Improvement and ResearchCapital's Funds for Health Improvement and Research260https://www.ebi.ac.uk/biostudies/studies/S-EPMC11295486biostudies-literatureUnknown28(1)<h4>Background</h4>This study aimed to explore the characteristics of abnormal regional resting-state functional magnetic resonance imaging (rs-fMRI) activity in comatose patients in the early period after cardiac arrest (CA), and to investigate their relationships with neurological outcomes. We also explored the correlations between jugular venous oxygen saturation (SjvO2) and rs-fMRI activity in resuscitated comatose patients. We also examined the relationship between the amplitude of the N20-baseline and the rs-fMRI activity within the intracranial conduction pathway of somatosensory evoked potentials (SSEPs).<h4>Methods</h4>Between January 2021 and January 2024, eligible post-resuscitated patients were screened to undergo fMRI examination. The amplitude of low-frequency fluctuation (ALCritical care (London, England)Alteration in early resting‑state functional MRI activity in comatose survivors of cardiac arrest: a prospective cohort study.PMC1129548682072136CFH 2022-1-2032Discipline Leader-01-01DFL20240302Tang ZHang CShan ZAn LWang TWang XZhang LYang QShao RYu JfalseAlteration in early resting‑state functional MRI activity in comatose survivors of cardiac arrest: a prospective cohort study.<h4>Background</h4>This study aimed to explore the characteristics of abnormal regional resting-state functional magnetic resonance imaging (rs-fMRI) activity in comatose patients in the early period after cardiac arrest (CA), and to investigate their relationships with neurological outcomes. We also explored the correlations between jugular venous oxygen saturation (SjvO2) and rs-fMRI activity in resuscitated comatose patients. We also examined the relationship between the amplitude of the N20-baseline and the rs-fMRI activity within the intracranial conduction pathway of somatosensory evoked potentials (SSEPs).<h4>Methods</h4>Between January 2021 and January 2024, eligible post-resuscitated patients were screened to undergo fMRI examination. The amplitude of low-frequency fluctuation (AL2024-01-01T00:00:00Z2024 Aug2026-06-03T00:39:11.588Z2025-02-19T02:27:28.972ZS-EPMC112954863909588410.1186/s13054-024-05045-4