{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["7(8)"],"submitter":["Ronellenfitsch U"],"pubmed_abstract":["<h4>Importance</h4>The prognosis of patients with adenocarcinoma of the esophagus and esophagogastric junction (AEG) is poor. From current evidence, it remains unclear to what extent preoperative chemoradiotherapy (CRT) or preoperative and/or perioperative chemotherapy achieve better outcomes than surgery alone.<h4>Objective</h4>To assess the association of preoperative CRT and preoperative and/or perioperative chemotherapy in patients with AEG with overall survival and other outcomes.<h4>Data sources</h4>Literature search in PubMed, Cochrane Library, Cumulative Index to Nursing and Allied Health Literature, ClinicalTrials.gov, and International Clinical Trials Registry Platform was performed from inception to April 21, 2023.<h4>Study selection</h4>Two blinded reviewers screened for random"],"journal":["JAMA network open"],"pagination":["e2425581"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11297377"],"repository":["biostudies-literature"],"pubmed_title":["Preoperative Chemoradiotherapy vs Chemotherapy for Adenocarcinoma of the Esophagogastric Junction: A Network Meta-Analysis."],"pmcid":["PMC11297377"],"pubmed_authors":["Nilsson M","Kieser M","Eyck BM","Cunningham D","Shi Q","Vey JA","Lutz M","Michl P","Grilli M","Lordick F","Proctor T","Vordermark D","Michalski CW","Ronellenfitsch U","Seide S","Barbier E","Nankivell M","Hofheinz RD","Stahl M","Urba S","Bass GA","Langley R","Walsh TN","Friedrichs J","van Lanschot J","Ychou M","Kleeff J","Shah MA","Burmeister B","Mauer M","Klevebro F"],"additional_accession":[]},"is_claimable":false,"name":"Preoperative Chemoradiotherapy vs Chemotherapy for Adenocarcinoma of the Esophagogastric Junction: A Network Meta-Analysis.","description":"<h4>Importance</h4>The prognosis of patients with adenocarcinoma of the esophagus and esophagogastric junction (AEG) is poor. From current evidence, it remains unclear to what extent preoperative chemoradiotherapy (CRT) or preoperative and/or perioperative chemotherapy achieve better outcomes than surgery alone.<h4>Objective</h4>To assess the association of preoperative CRT and preoperative and/or perioperative chemotherapy in patients with AEG with overall survival and other outcomes.<h4>Data sources</h4>Literature search in PubMed, Cochrane Library, Cumulative Index to Nursing and Allied Health Literature, ClinicalTrials.gov, and International Clinical Trials Registry Platform was performed from inception to April 21, 2023.<h4>Study selection</h4>Two blinded reviewers screened for random","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Aug","modification":"2026-06-01T22:18:11.858Z","creation":"2026-05-22T03:08:00.19Z"},"accession":"S-EPMC11297377","cross_references":{"pubmed":["39093560"],"doi":["10.1001/jamanetworkopen.2024.25581"]}}