biostudies-literatureUnknown69(8)Goodfellow LTGiven the important role of patient-ventilator assessments in ensuring the safety and efficacy of mechanical ventilation, a team of respiratory therapists and a librarian used Grading of Recommendations, Assessment, Development, and Evaluation methodology to make the following recommendations: (1) We recommend assessment of plateau pressure to ensure lung-protective ventilator settings (strong recommendation, high certainty); (2) We recommend an assessment of tidal volume (V_T) to ensure lung-protective ventilation (4-8 mL/kg/predicted body weight) (strong recommendation, high certainty); (3) We recommend documenting V_T as mL/kg predicted body weight (strong recommendation, high certainty); (4) We recommend an assessment of PEEP and auto-PEEP (strong recommendation, hiRespiratory care1042-1054https://www.ebi.ac.uk/biostudies/studies/S-EPMC11298231biostudies-literatureAARC Clinical Practice Guideline: Patient-Ventilator Assessment.PMC11298231Varekojis SMHess DRLaVita CJGlogowski JTGoodfellow LTMiller AGfalseAARC Clinical Practice Guideline: Patient-Ventilator Assessment.Given the important role of patient-ventilator assessments in ensuring the safety and efficacy of mechanical ventilation, a team of respiratory therapists and a librarian used Grading of Recommendations, Assessment, Development, and Evaluation methodology to make the following recommendations: (1) We recommend assessment of plateau pressure to ensure lung-protective ventilator settings (strong recommendation, high certainty); (2) We recommend an assessment of tidal volume (V_T) to ensure lung-protective ventilation (4-8 mL/kg/predicted body weight) (strong recommendation, high certainty); (3) We recommend documenting V_T as mL/kg predicted body weight (strong recommendation, high certainty); (4) We recommend an assessment of PEEP and auto-PEEP (strong recommendation, hi2024-01-01T00:00:00Z2024 Jul2026-03-18T13:29:57.794Z2025-08-18T09:54:10.878ZS-EPMC112982313904814810.4187/respcare.12007