{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14"],"submitter":["Shen J"],"pubmed_abstract":["<h4>Introduction</h4>Desmoid tumor (DT) is a rare proliferative disease occurring in connective tissues, characterized by high infiltration and recurrence rates. While surgery remains the primary treatment, its recurrence risk is high, and some extra-abdominal desmoid tumors are inoperable due to their locations. Despite attempts with radiotherapy and systemic therapy, the efficacy remains limited.<h4>Methods</h4>We used low-power cumulative high-intensity focused ultrasound (HIFU) therapy as an initial treatment for desmoid tumor patients either ineligible or unwilling for surgery. Low-power cumulative HIFU employs slower heat accumulation and diffusion, minimizing damage to surrounding tissues while enhancing efficacy.<h4>Results</h4>Fifty-seven non-FAP desmoid tumor patients, previously"],"journal":["Frontiers in oncology"],"pagination":["1388302"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11298426"],"repository":["biostudies-literature"],"pubmed_title":["Initial treatment for surgery-naive desmoid tumors by high intensity focused ultrasound."],"pmcid":["PMC11298426"],"pubmed_authors":["Hu C","Shen J","Wu L","Hu X","Zhong X","Zhao J","Shen H","Xie S"],"additional_accession":[]},"is_claimable":false,"name":"Initial treatment for surgery-naive desmoid tumors by high intensity focused ultrasound.","description":"<h4>Introduction</h4>Desmoid tumor (DT) is a rare proliferative disease occurring in connective tissues, characterized by high infiltration and recurrence rates. While surgery remains the primary treatment, its recurrence risk is high, and some extra-abdominal desmoid tumors are inoperable due to their locations. Despite attempts with radiotherapy and systemic therapy, the efficacy remains limited.<h4>Methods</h4>We used low-power cumulative high-intensity focused ultrasound (HIFU) therapy as an initial treatment for desmoid tumor patients either ineligible or unwilling for surgery. Low-power cumulative HIFU employs slower heat accumulation and diffusion, minimizing damage to surrounding tissues while enhancing efficacy.<h4>Results</h4>Fifty-seven non-FAP desmoid tumor patients, previously","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024","modification":"2025-06-01T00:59:24.258Z","creation":"2025-06-01T00:59:24.258Z"},"accession":"S-EPMC11298426","cross_references":{"pubmed":["39104718"],"doi":["10.3389/fonc.2024.1388302"]}}