biostudies-literatureHuang YFujian Minimally Invasive Medical Center (Thoracic Surgery), Chinae082412https://www.ebi.ac.uk/biostudies/studies/S-EPMC11298735biostudies-literatureUnknown14(8)<h4>Introduction</h4>Significant numbers of patients undergoing minimally invasive lung surgery develop chronic symptoms such as chronic pain and chronic cough after surgery, which may lead to a reduced quality of life (QoL). Despite this, there remains a dearth of high-quality prospective studies on this topic. Therefore, our study aims to systematically investigate the incidence and progression of long-term chronic symptoms following minimally invasive lung surgery, as well as changes in patient's psychological status and long-term QoL.<h4>Methods</h4>This is a single-centre, observational, prospective study that included patients with stage I non-small cell lung cancer or benign lesions. Prior to surgery, patients' baseline levels of chronic pain, chronic cough and sleep will be documenBMJ openPostoperative chronic operation-related symptoms after minimally invasive lung surgery: a prospective observational protocol.PMC11298735N/AWu ZHuang YChen MLiu PZheng BZhang SChen CfalsePostoperative chronic operation-related symptoms after minimally invasive lung surgery: a prospective observational protocol.<h4>Introduction</h4>Significant numbers of patients undergoing minimally invasive lung surgery develop chronic symptoms such as chronic pain and chronic cough after surgery, which may lead to a reduced quality of life (QoL). Despite this, there remains a dearth of high-quality prospective studies on this topic. Therefore, our study aims to systematically investigate the incidence and progression of long-term chronic symptoms following minimally invasive lung surgery, as well as changes in patient's psychological status and long-term QoL.<h4>Methods</h4>This is a single-centre, observational, prospective study that included patients with stage I non-small cell lung cancer or benign lesions. Prior to surgery, patients' baseline levels of chronic pain, chronic cough and sleep will be documen2024-01-01T00:00:00Z2024 Aug2026-06-08T06:28:18.761Z2026-06-08T03:14:26.437ZS-EPMC112987353909730410.1136/bmjopen-2023-082412