biostudies-literatureUnknown13(8)Das T<h4>Purpose</h4>We constructed a clinical clue-based algorithm to identify the microbiology-positive post-cataract surgery endophthalmitis.<h4>Methods</h4>The Endophthalmitis Infectivity Measurement Algorithm (EIMA) was constructed using presenting Snellen vision (Letter score [LS]) and Inflammation Score (IS, from the cornea, anterior chamber, iris, and vitreous). Retrospective data (70% for training; 30% for testing) was fitted into CHAID (Chi-squared Automatic Interaction Detection). EIMA was validated with prospective data. EIMA-categorized disease severity was weighed against the symptom duration to detect infecting micro-organisms.<h4>Results</h4>EIMA was constructed from 1444 retrospective data. The average LS was 6.03 ± 12.11, median IS was 14 (8-24), and culture positivity was 38%Translational vision science & technology10https://www.ebi.ac.uk/biostudies/studies/S-EPMC11316448biostudies-literatureDesign and Validation of Endophthalmitis Infectivity Measurement Algorithm in Post Cataract Acute Endophthalmitis: EMS Report No. 6.PMC11316448Behera UCJoseph JDave VPDas TPandya RKapoor ABelenje ASahoo JPandey SfalseDesign and Validation of Endophthalmitis Infectivity Measurement Algorithm in Post Cataract Acute Endophthalmitis: EMS Report No. 6.<h4>Purpose</h4>We constructed a clinical clue-based algorithm to identify the microbiology-positive post-cataract surgery endophthalmitis.<h4>Methods</h4>The Endophthalmitis Infectivity Measurement Algorithm (EIMA) was constructed using presenting Snellen vision (Letter score [LS]) and Inflammation Score (IS, from the cornea, anterior chamber, iris, and vitreous). Retrospective data (70% for training; 30% for testing) was fitted into CHAID (Chi-squared Automatic Interaction Detection). EIMA was validated with prospective data. EIMA-categorized disease severity was weighed against the symptom duration to detect infecting micro-organisms.<h4>Results</h4>EIMA was constructed from 1444 retrospective data. The average LS was 6.03 ± 12.11, median IS was 14 (8-24), and culture positivity was 38%2024-01-01T00:00:00Z2024 Aug2025-04-18T20:07:04.305Z2025-04-07T07:56:34.042ZS-EPMC113164483911057510.1167/tvst.13.8.10