{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["43(9)"],"submitter":["Lees EA"],"funding":["Wellcome Trust"],"pubmed_abstract":["<h4>Background</h4>During autumn/winter 2022, UK pediatricians reported an unseasonal increase in invasive group A streptococcal infections; a striking proportion presenting with pneumonia with parapneumonic effusion.<h4>Methods</h4>Clinicians across the United Kingdom were requested to submit pseudonymized clinical data using a standardized report form for children (<16 years) admitted between September 30, 2022 and February 17, 2023, with microbiologically confirmed group A streptococcal pneumonia with parapneumonic effusion.<h4>Results</h4>From 185 cases submitted, the median patient age was 4.4 years, and 163 (88.1%) were previously healthy. Respiratory viral coinfection was detected on admission for 101/153 (66.0%) children using extended respiratory pathogen polymerase chain reaction"],"journal":["The Pediatric infectious disease journal"],"pagination":["841-850"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11319078"],"repository":["biostudies-literature"],"pubmed_title":["Epidemiology and Management of Pediatric Group A Streptococcal Pneumonia With Parapneumonic Effusion: An Observational Study."],"pmcid":["PMC11319078"],"pubmed_authors":["Williams TC","Sinha A","Haynes N","Fidler K","Brampton R","Gordon S","Koo S","Hoskyns L","Hatcher J","Bakar A","Blomquist P","Adesina A","Everitt L","Carveth Johnson T","Fitzgerald F","Watson G","Pillai A","Finlay J","Dixon G","Speirs L","Lyall H","Lees EA","Marlow R","Drysdale S","Pollock L","Hey A","Bernatoniene J","McMaster P","Longbottom K","Whittaker E","Oakley J","Llano M","Lamagni T","Group A Streptococcal Disease Consortium","Devesa P","Alexander N","Hayes E","Jones C","Garde A","Elghuwael I","Inwald D","Bamford A","Hull J","Ives A","Kavanagh S","Kirk N","Kent A","Kilpatrick C","Sang TC","Rutter M","Pike K","Randle E","Smith A","Mitting R","Walsh L","Riordan A","Lorenzetti G","Kuruvilla G","Bridge T","Kumar D","Kadambari S","Bowen SJ","Vergnano S","Kuek S","Hormigo I","McShane TD","Bandi S","Brugha R","Bycroft T","Farah S"],"additional_accession":[]},"is_claimable":false,"name":"Epidemiology and Management of Pediatric Group A Streptococcal Pneumonia With Parapneumonic Effusion: An Observational Study.","description":"<h4>Background</h4>During autumn/winter 2022, UK pediatricians reported an unseasonal increase in invasive group A streptococcal infections; a striking proportion presenting with pneumonia with parapneumonic effusion.<h4>Methods</h4>Clinicians across the United Kingdom were requested to submit pseudonymized clinical data using a standardized report form for children (<16 years) admitted between September 30, 2022 and February 17, 2023, with microbiologically confirmed group A streptococcal pneumonia with parapneumonic effusion.<h4>Results</h4>From 185 cases submitted, the median patient age was 4.4 years, and 163 (88.1%) were previously healthy. Respiratory viral coinfection was detected on admission for 101/153 (66.0%) children using extended respiratory pathogen polymerase chain reaction","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Sep","modification":"2025-04-19T14:50:08.588Z","creation":"2025-04-19T14:50:08.588Z"},"accession":"S-EPMC11319078","cross_references":{"pubmed":["38900036"],"doi":["10.1097/INF.0000000000004418"]}}