{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Merhar SL"],"funding":["NICHD NIH HHS","NIH HHS"],"pagination":["976-984"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11320328"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["178(10)"],"pubmed_abstract":["<h4>Importance</h4>Infants with neonatal opioid withdrawal syndrome (NOWS) cared for with the Eat, Sleep, Console (ESC) care approach receive less pharmacologic treatment and have shorter hospital stays compared to usual care with the Finnegan Neonatal Abstinence Scoring Tool, but the effects of these approaches on feeding and weight are unknown.<h4>Objective</h4>To evaluate feeding practices and weight trajectories in infants cared for with ESC vs usual care.<h4>Design, setting, and participants</h4>ESC-NOW is a cluster randomized trial of infants with NOWS born at 36 weeks' gestation or later at 26 US hospitals from September 2020 to March 2022. Each site transitioned from usual care to ESC (the study intervention) at a randomized time. Feeding was per site practice and not specified by "],"journal":["JAMA pediatrics"],"pubmed_title":["Infant Feeding and Weight Trajectories in the Eat, Sleep, Console Trial: A Secondary Analysis of a Randomized Clinical Trial."],"pmcid":["PMC11320328"],"funding_grant_id":["UG1 OD024956","U01 HD036790","U24 HD095254"],"pubmed_authors":["Ros-Demarize R","Gibson T","Hu Z","Bracken M","Perkins T","Grisby C","Summe V","Lutz A","Pulsifer A","Wright T","Mackley A","Malloch L","Hines D","Trochinski L","Kern A","Schibler K","Gocial S","Steinhorn R","Tallikar A","Lloyd SL","Dummula K","Newton J","Russell D","Horn E","Hahn D","Lakshminrusimha S","Slaughter JL","Walsh MC","Sanders S","Hartley-McAndrews ME","Diles M","Christ L","Jensen RL","Kish P","Williams S","White K","Hamilton J","Miller K","Angelidou A","Howard D","Purnell J","Parga-Belinkie J","Howell MP","McKeown K","Santos M","Kirker K","Amaya M","Turner E","Kilkenny T","White R","Balakrishnan M","Ross J","Luzader P","McCarty T","Castellone D","Hogden LA","Volker P","Riccio J","Donato J","Todd J","Miner C","Boyle RJ","Wellman R","Dhawan M","White JR","Bradley L","Driscoll S","Stepp J","Fung CM","Rolfes L","Newman JE","Haddix A","DeSpain M","Gier J","Smith PB","Sanchez PJ","Brant M","Goldstein J","Muniyappa B","Schomaker E","Merhar SL","McDowell A","Chlon C","Boyd J","Ferrin M","Shaikh SK","Kowel K","Martino AL","Rieper M","Nelson J","Li E","Cobe C","Azuma K","Staton T","Henning MM","Jones R","Jones S","Quigley E","Crowley M","Guillet R","Johnson M","Higgins RD","Scott A","Sullivan J","Banks-Johnson C","Pickett J","Petersen B","Reynolds AM","Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network National Institutes of Health Environmental Influences on Child Health Outcomes Program Institutional Development Award States Pediatric Clinical Trials Network","Allen MC","Keels EL","Brodkorb A","Kertesz M","Snowden JN","Jackson J","Karlin J","Walsh T","McCool J","Hart S","Moore S","Bann CM","Wong Ramsey K","Wilson Archer S","Mancini T","Anderson B","Pastore N","Nascimbeni A","Van Muyden S","Loertscher MC","Pastore J","Harris K","Maxwell JR","Zachritz W","Wilson S","Ray L","Weiner SJ","Eichenwald EC","Hibbs AM","Ounpraseuth ST","Simon AE","Slaughter A","Rice W","Braswell EF","Mars M","Coleman K","Krokovich L","Zaterka-Baxter KM","Shuttleworth KL","Palmer JN","Wadman J","Newman S","Marzec L","Amiotte A","DeSantis B","Edwards K","MacMillan K","DeSantis H","Paul DA","Reedy R","Taosaka J","Neal C","Ziolkowski K","Hanlon C","Frailey E","Scorsone AM","Telang SD","Ferri A","D'Angio C","Crawford MM","Erner JL","Hubberd DE","Alur R","Harvey S","O'Donnell Auman J","Cross M","Raissy H","Kong A","Brei L","Cathey K","Clemons T","Summer A","Pritchett D","Kent A","Leblond D","Reynolds V","Serio K","Weiner J","Lee JY","Kovalcik JB","Simon A","Terrano D","Roberts N","Baker S","Waldvogel J","Donahue N","Small K","Barber J","Ford K","Froese P","Richards P","Watson S","Hanniman M","Carnohan A","Naik T","Madden C","Gambacorta MK","Clarke L","D'Alton ME","Annett RD","Voelker K","Gleason CA","Foster K","McCalmont K","Schmidt T","Baserga M","Schumacher B","Hammond K","Schumacher A","Benninger K","Freeman M","Blaisdell CJ","Kunk R","Strike H","Sheehan Desselle F","Young LW","Ohls RK","Griffith M","Mioneo Brady A","Moreland M","Anderson-Berry A","Kneusel M","Ziegelmeyer A","Pahl A","Whalen BL","Baack ML","Rau CA","Shakib J","McAlmon K","Solpietro S","Edwards KD","Rodriguez A","Fratesi E","McAllister JM","Childres J","Resetar M","Powers C","Walker C","Sundquist Beauman S","McKee KG","Atz AM","Hubberd A","Majure JM","Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network National Institutes of Health Environmental Influences on Child Health Outcomes Program Institutional Development Award States Pediatric Clinical Tri","Beiersdorfer T","Robinson P","Knox J","Smith E","Smith K","McGrath KM","Devlin LA","Sarraf LA","Brown J","Gabrio J","Elenkiwich C","Orland R","Das A","Loudermilk MK","Tucker L","Brown R"],"additional_accession":[]},"is_claimable":false,"name":"Infant Feeding and Weight Trajectories in the Eat, Sleep, Console Trial: A Secondary Analysis of a Randomized Clinical Trial.","description":"<h4>Importance</h4>Infants with neonatal opioid withdrawal syndrome (NOWS) cared for with the Eat, Sleep, Console (ESC) care approach receive less pharmacologic treatment and have shorter hospital stays compared to usual care with the Finnegan Neonatal Abstinence Scoring Tool, but the effects of these approaches on feeding and weight are unknown.<h4>Objective</h4>To evaluate feeding practices and weight trajectories in infants cared for with ESC vs usual care.<h4>Design, setting, and participants</h4>ESC-NOW is a cluster randomized trial of infants with NOWS born at 36 weeks' gestation or later at 26 US hospitals from September 2020 to March 2022. Each site transitioned from usual care to ESC (the study intervention) at a randomized time. Feeding was per site practice and not specified by ","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Oct","modification":"2026-05-29T15:16:03.532Z","creation":"2026-04-08T05:13:25.677Z"},"accession":"S-EPMC11320328","cross_references":{"pubmed":["39133505"],"doi":["10.1001/jamapediatrics.2024.2578"]}}