biostudies-literatureHashimoto HOsaka UniversityJapan Society for the Promotion of Science2851-2858https://www.ebi.ac.uk/biostudies/studies/S-EPMC11322201biostudies-literatureUnknown40(9)<h4>Introduction</h4>Most myelomeningocele (MMC) cases present with ventriculomegaly or hydrocephalus, yet a comprehensive volumetric assessment of MMC intracranial structures is lacking. This study aimed to provide baseline data on intracranial structural volumes immediately after birth in MMC infants who underwent repair surgeries after birth (postnatal repair).<h4>Methods</h4>In this retrospective single-center study, we analyzed 52 MMC infants undergoing postnatal repair, utilizing head computed tomography scans at birth for volumetric assessment. Intracranial volume (ICV), lateral ventricles volume (LVV), choroid plexus volume (CPV), and posterior cranial fossa volume (PCFV) were measured. Hydrocephalus was classified into no hydrocephalus, progressive hydrocephalus, and hydrocephalusChild's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryIntracranial volumetric evaluation in postnatally repaired myelomeningocele infants.PMC11322201JP21K16629Chiba YIrizato NTakemoto OHashimoto HfalseIntracranial volumetric evaluation in postnatally repaired myelomeningocele infants.<h4>Introduction</h4>Most myelomeningocele (MMC) cases present with ventriculomegaly or hydrocephalus, yet a comprehensive volumetric assessment of MMC intracranial structures is lacking. This study aimed to provide baseline data on intracranial structural volumes immediately after birth in MMC infants who underwent repair surgeries after birth (postnatal repair).<h4>Methods</h4>In this retrospective single-center study, we analyzed 52 MMC infants undergoing postnatal repair, utilizing head computed tomography scans at birth for volumetric assessment. Intracranial volume (ICV), lateral ventricles volume (LVV), choroid plexus volume (CPV), and posterior cranial fossa volume (PCFV) were measured. Hydrocephalus was classified into no hydrocephalus, progressive hydrocephalus, and hydrocephalus2024-01-01T00:00:00Z2024 Sep2025-04-21T22:04:02.133Z2025-04-05T18:36:00.872ZS-EPMC113222013871460510.1007/s00381-024-06444-2