biostudies-literatureStarr MCNCATS NIH HHSNIDDK NIH HHSNHLBI NIH HHSGerber FoundationNIGMS NIH HHS406-415.e1https://www.ebi.ac.uk/biostudies/studies/S-EPMC11324858biostudies-literatureUnknown84(4)<h4>Rationale & objective</h4>There are limited studies describing the epidemiology and outcomes in children and young adults receiving continuous kidney replacement therapy (CKRT). We aimed to describe associations between patient characteristics, CKRT prescription, and survival.<h4>Study design</h4>Retrospective multicenter cohort study.<h4>Setting & participants</h4>980 patients aged from birth to 25 years who received CKRT between 2015 and 2021 at 1 of 32 centers in 7 countries participating in WE-ROCK (Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Diseases).<h4>Exposure</h4>CKRT for acute kidney injury or volume overload.<h4>Outcomes</h4>Death before intensive care unit (ICU) discharge.<h4>Analytical approach</h4>Descriptive statistics.<h4>Results</h4>MedAmerican journal of kidney diseases : the official journal of the National Kidney FoundationContinuous Kidney Replacement Therapy and Survival in Children and Young Adults: Findings From the Multinational WE-ROCK Collaborative.PMC11324858K23 HL168362K12 TR004415UL1 TR001425K23 GM151444R13 DK137550Marinari ERicci ZSantiago Lozano MJUber AMColosimo DShin HSSoranno DECortina GHill-Horowitz TAlhamoud IGorga SMMuff-Luett MArikan AANavazo SMStarr MCRumlow ZAMartin SDMah KEGist KMBigelow AMGuzzi FRaggi VSolomon SDing KLDamian MAWorldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease (WE-ROCK) CollaborativeKwiatkowski DMNeumayr TMAlobaidi RGuzzo ISlagle CPinto MHarvey EKorn SShih WVHaga TLequier LO'Rourke ASelewski DTInthavong HLee JDolan KJStrong AEDeAbreu GFernandez Lafever SNHasson DCWebb TCiccia EMenon SBarhight MSee EZappitelli MBasalely AKrallman KAZangla EEBalani SMottes TANamachivayam SSerpe CSerratore ADeep AOllberding NJGelbart BMorgan CBottari GKessel ACappoli AReynaud SKaddourah AAhern ENhan JSrivastava RFuhrman DYQutob DKakajiwala AMohamed THShah AVan Wyk BThadani SVZang HJoseph CKia TMStanski NLAnton-Martin PCollins MStenson EKTaylor SAfalseContinuous Kidney Replacement Therapy and Survival in Children and Young Adults: Findings From the Multinational WE-ROCK Collaborative.<h4>Rationale & objective</h4>There are limited studies describing the epidemiology and outcomes in children and young adults receiving continuous kidney replacement therapy (CKRT). We aimed to describe associations between patient characteristics, CKRT prescription, and survival.<h4>Study design</h4>Retrospective multicenter cohort study.<h4>Setting & participants</h4>980 patients aged from birth to 25 years who received CKRT between 2015 and 2021 at 1 of 32 centers in 7 countries participating in WE-ROCK (Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Diseases).<h4>Exposure</h4>CKRT for acute kidney injury or volume overload.<h4>Outcomes</h4>Death before intensive care unit (ICU) discharge.<h4>Analytical approach</h4>Descriptive statistics.<h4>Results</h4>Med2024-01-01T00:00:00Z2024 Oct2026-06-06T21:26:46.584Z2025-04-04T18:53:26.465ZS-EPMC113248583836495610.1053/j.ajkd.2023.12.017