{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Stamellou E"],"funding":["Deutsche Forschungsgemeinschaft"],"pagination":["sfae230"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11324945"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["17(8)"],"pubmed_abstract":["<h4>Background</h4>The importance of albuminuria as opposed to proteinuria in predicting kidney outcomes in primary immunoglobulin A nephropathy (IgAN) is not well established.<h4>Methods</h4>From 2010 to 2012, 421 patients with biopsy-proven IgAN have been enrolled into the German Chronic Kidney Disease (GCKD) cohort, a prospective observational cohort study (<i>N</i> = 5217). Adjudicated endpoints include a composite kidney endpoint (CKE) consisting of eGFR decline >40%, eGFR <15 ml/min/1.73 m<sup>2</sup> and initiation of kidney replacement therapy; the individual components of the CKE; and combined major adverse cardiac events (MACE), including non-fatal myocardial infarction, non-fatal stroke and all-cause mortality. The associations between the incidence of CKE and baseline factors, "],"journal":["Clinical kidney journal"],"pubmed_title":["Long-term outcomes of patients with IgA nephropathy in the German CKD cohort."],"pmcid":["PMC11324945"],"funding_grant_id":["445703531"],"pubmed_authors":["Schiffer M","Bauer B","Meder S","Eckardt KU","Schaeffner E","Weissensteiner H","Kronenberg F","Wanner C","Kotsis F","Saritas T","Bechtel-Walz W","Forer L","Floege J","Mitsch E","Schmidt-Ott K","Stamellou E","Schonherr S","Gronwald W","Kottgen A","Ekici AB","Hendry B","Kollerits B","Prokosch HU","Reis A","Beck A","Alberth-Schmidt U","Busch M","Raschenberger J","Barthlein B","Schultheiß UT","Theisen K","Baid-Agrawal S","Oefner P","Reinhard U","Mercer A","Becker S","Schmid M","Steiner A","Schneider MP","Kramann R","Zeier M","Nadal J","Wolf G","Walz G","Krane V","Aykac M","Sitter T","Moeller MJ","Meiselbach H","Sommerer C","Seikrit C","Marschall S","GCKD study investigators","Weigel A"],"additional_accession":[]},"is_claimable":false,"name":"Long-term outcomes of patients with IgA nephropathy in the German CKD cohort.","description":"<h4>Background</h4>The importance of albuminuria as opposed to proteinuria in predicting kidney outcomes in primary immunoglobulin A nephropathy (IgAN) is not well established.<h4>Methods</h4>From 2010 to 2012, 421 patients with biopsy-proven IgAN have been enrolled into the German Chronic Kidney Disease (GCKD) cohort, a prospective observational cohort study (<i>N</i> = 5217). Adjudicated endpoints include a composite kidney endpoint (CKE) consisting of eGFR decline >40%, eGFR <15 ml/min/1.73 m<sup>2</sup> and initiation of kidney replacement therapy; the individual components of the CKE; and combined major adverse cardiac events (MACE), including non-fatal myocardial infarction, non-fatal stroke and all-cause mortality. The associations between the incidence of CKE and baseline factors, ","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Aug","modification":"2025-05-18T12:13:37.746Z","creation":"2025-04-05T10:09:35.353Z"},"accession":"S-EPMC11324945","cross_references":{"pubmed":["39149090"],"doi":["10.1093/ckj/sfae230"]}}