{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Gao D"],"funding":["National Natural Science Foundation of China"],"pagination":["e079879"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11328640"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(6)"],"pubmed_abstract":["Introduction
Intracerebral haemorrhage (ICH) is a neurological emergency with high morbidity and mortality, and current treatment is limited. Emerging evidence has reported that statins can exert neuroprotective effects in cerebrovascular diseases. However, most of the published clinical studies are retrospective. Therefore, it is important to conduct a prospective randomised controlled trial to further validate the efficacy and safety of statins in patients with ICH.Methods and analysis
The present study is performed at Xuan Wu Hospital Capital Medical University, Beijing Fengtai You'anmen Hospital and Shunping County Hospital, Hebei Province. The target number of patients is 98. Eligible patients are randomly assigned in a 1:1 ratio to the statins group or the control gro"],"journal":["BMJ open"],"pubmed_title":["Statins for neuroprotection in spontaneous intracerebral haemorrhage (STATIC): protocol for a multicentre, prospective and randomised controlled trial."],"pmcid":["PMC11328640"],"funding_grant_id":["82271507","82071468"],"pubmed_authors":["Ji X","Zhang Y","Jiang X","Wu C","Chu X","Niu L","Bao S","Yan H","Gao D"],"additional_accession":[]},"is_claimable":false,"name":"Statins for neuroprotection in spontaneous intracerebral haemorrhage (STATIC): protocol for a multicentre, prospective and randomised controlled trial.","description":"Introduction
Intracerebral haemorrhage (ICH) is a neurological emergency with high morbidity and mortality, and current treatment is limited. Emerging evidence has reported that statins can exert neuroprotective effects in cerebrovascular diseases. However, most of the published clinical studies are retrospective. Therefore, it is important to conduct a prospective randomised controlled trial to further validate the efficacy and safety of statins in patients with ICH.Methods and analysis
The present study is performed at Xuan Wu Hospital Capital Medical University, Beijing Fengtai You'anmen Hospital and Shunping County Hospital, Hebei Province. The target number of patients is 98. Eligible patients are randomly assigned in a 1:1 ratio to the statins group or the control gro","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jun","modification":"2026-06-14T05:28:23.624Z","creation":"2026-06-14T03:08:40.149Z"},"accession":"S-EPMC11328640","cross_references":{"pubmed":["38908848"],"doi":["10.1136/bmjopen-2023-079879"]}}