{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["19(8)"],"submitter":["Wright J"],"pubmed_abstract":["<h4>Introduction</h4>The incidence of varicella in Canada has decreased by almost 99% since vaccination was introduced. However, variation in the timing and eligibility of vaccination programs across the country has resulted in some cohorts being under-vaccinated and therefore potentially susceptible to infection.<h4>Methods</h4>We used nationally representative specimens from the Biobank of Statistics Canada's Canadian Health Measures Survey (CHMS) as well as residual specimens from Ontario collected between 2009-2014 to estimate population immunity across age-groups and geography, and identify any groups at increased risk of varicella infection.<h4>Results</h4>The weighted proportion of specimens with antibody levels above the threshold of protection was 93.6% (95% CI: 92.4, 95.0). Prote"],"journal":["PloS one"],"pagination":["e0309154"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11332944"],"repository":["biostudies-literature"],"pubmed_title":["Population immunity to varicella in Canada: A Canadian Immunization Research Network (CIRN) study."],"pmcid":["PMC11332944"],"pubmed_authors":["Crowcroft N","Hatchette T","Perez-Iratxeta C","Severini A","Gubbay J","Joh E","Wilson SE","Buchan SA","Ward BJ","Serhir B","Wright J","McLachlan E","Deeks SL","Bolotin S","Hughes SL","Brisson M","Osman S","Halperin SA"],"additional_accession":[]},"is_claimable":false,"name":"Population immunity to varicella in Canada: A Canadian Immunization Research Network (CIRN) study.","description":"<h4>Introduction</h4>The incidence of varicella in Canada has decreased by almost 99% since vaccination was introduced. However, variation in the timing and eligibility of vaccination programs across the country has resulted in some cohorts being under-vaccinated and therefore potentially susceptible to infection.<h4>Methods</h4>We used nationally representative specimens from the Biobank of Statistics Canada's Canadian Health Measures Survey (CHMS) as well as residual specimens from Ontario collected between 2009-2014 to estimate population immunity across age-groups and geography, and identify any groups at increased risk of varicella infection.<h4>Results</h4>The weighted proportion of specimens with antibody levels above the threshold of protection was 93.6% (95% CI: 92.4, 95.0). Prote","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024","modification":"2025-05-18T12:13:35.742Z","creation":"2025-05-18T12:13:35.742Z"},"accession":"S-EPMC11332944","cross_references":{"pubmed":["39159217"],"doi":["10.1371/journal.pone.0309154"]}}