{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14(8)"],"submitter":["Lu CW"],"pubmed_abstract":["<h4>Introduction</h4>Generalized pustular psoriasis (GPP) is a rare and severe psoriasis subtype characterized by the rapid onset of coalescing sterile pustules over broad body areas and systemic inflammation. Data on its clinical course and outcomes in Taiwan are limited. We evaluated the clinical profile and outcomes of patients with GPP flares in Taiwan.<h4>Methods</h4>This retrospective analysis included adult patients with moderate-to-severe GPP flares occurring in January 2008-December 2021. Data were extracted from medical charts and electronic health records in the Chang Gung Research Database. Statistical analyses were performed using SAS for Windows (version 9.4). Multivariate Poisson regression models were built to investigate different predictors of GPP flare rate.<h4>Results</"],"journal":["Dermatology and therapy"],"pagination":["2261-2275"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11333409"],"repository":["biostudies-literature"],"pubmed_title":["Clinical Characteristics and Disease Burden of Patients with Moderate-to-Severe Generalized Pustular Psoriasis Flares in Taiwan."],"pmcid":["PMC11333409"],"pubmed_authors":["Wang CW","Tseng CY","Chi CC","Huang YH","Chung WH","Lee CH","Hui RC","Lin FJ","Chen CB","Lin SH","Lu CW"],"additional_accession":[]},"is_claimable":false,"name":"Clinical Characteristics and Disease Burden of Patients with Moderate-to-Severe Generalized Pustular Psoriasis Flares in Taiwan.","description":"<h4>Introduction</h4>Generalized pustular psoriasis (GPP) is a rare and severe psoriasis subtype characterized by the rapid onset of coalescing sterile pustules over broad body areas and systemic inflammation. Data on its clinical course and outcomes in Taiwan are limited. We evaluated the clinical profile and outcomes of patients with GPP flares in Taiwan.<h4>Methods</h4>This retrospective analysis included adult patients with moderate-to-severe GPP flares occurring in January 2008-December 2021. Data were extracted from medical charts and electronic health records in the Chang Gung Research Database. Statistical analyses were performed using SAS for Windows (version 9.4). Multivariate Poisson regression models were built to investigate different predictors of GPP flare rate.<h4>Results</","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Aug","modification":"2025-04-26T21:14:35.956Z","creation":"2025-04-26T21:14:35.956Z"},"accession":"S-EPMC11333409","cross_references":{"pubmed":["39078583"],"doi":["10.1007/s13555-024-01228-7"]}}