{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Christian CS"],"funding":["Medical Research Council","Foreign, Commonwealth &amp; Development Office","National Institute for Health Research (NIHR)","Oxford Health Biomedical Research Centre","UK Research and Innovation","Wellcome Trust"],"pagination":["e082977"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11337707"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(8)"],"pubmed_abstract":["<h4>Introduction</h4>Poverty, HIV and perinatal depression represent a triple threat to public health in sub-Saharan Africa because of their combined negative effects on parenting and child development. In the resource-constrained context of low-income and middle-income countries, a lay-counsellor-delivered intervention that combines a psychological and parenting intervention could offer the potential to mitigate the consequences of perinatal depression while also optimising scarce resources for healthcare.Measuring the cost-effectiveness of such a novel intervention will help decision-makers to better understand the relative costs and effects associated with replicating the intervention, thereby supporting evidence-based decision-making. This protocol sets out the methodological framework"],"journal":["BMJ open"],"pubmed_title":["Protocol of a cost-effectiveness analysis of a combined intervention for depression and parenting compared with enhanced standard of care for perinatally depressed, HIV-positive women and their infants in rural South Africa."],"pmcid":["PMC11337707"],"funding_grant_id":["201433/Z/16/A","MR/P006965/1"],"pubmed_authors":["Rochat T","Stein A","Nkonki L","Christian CS","Desmond C","Hoegfeldt C","Dube S"],"additional_accession":[]},"is_claimable":false,"name":"Protocol of a cost-effectiveness analysis of a combined intervention for depression and parenting compared with enhanced standard of care for perinatally depressed, HIV-positive women and their infants in rural South Africa.","description":"<h4>Introduction</h4>Poverty, HIV and perinatal depression represent a triple threat to public health in sub-Saharan Africa because of their combined negative effects on parenting and child development. In the resource-constrained context of low-income and middle-income countries, a lay-counsellor-delivered intervention that combines a psychological and parenting intervention could offer the potential to mitigate the consequences of perinatal depression while also optimising scarce resources for healthcare.Measuring the cost-effectiveness of such a novel intervention will help decision-makers to better understand the relative costs and effects associated with replicating the intervention, thereby supporting evidence-based decision-making. This protocol sets out the methodological framework","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Aug","modification":"2025-04-04T03:10:24.196Z","creation":"2025-04-04T03:10:24.196Z"},"accession":"S-EPMC11337707","cross_references":{"pubmed":["39097310"],"doi":["10.1136/bmjopen-2023-082977"]}}