biostudies-literatureCuthbertson CCNHLBINIA NIH HHSNHLBI NIH HHSNational Cancer InstituteNCI NIH HHSNIHWHI NIH HHS108070https://www.ebi.ac.uk/biostudies/studies/S-EPMC11338699biostudies-literatureUnknown186<h4>Objective</h4>Accumulating more steps/day is associated with a lower risk of cancer mortality and composite cancer outcomes. However, less is known about the relationship of steps/day with the risk of multiple site-specific cancers.<h4>Methods</h4>This study included >22,000 women from the Women's Health Accelerometry Collaboration Cohort (2011-2022), comprised of women from the Women's Health Study and Women's Health Initiative Objective Physical Activity and Cardiovascular Health Study. Steps/day and step intensity were collected with accelerometry. Incident cancer cases and deaths were adjudicated. Stratified Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) of the associations of steps/day and step intensity with incident bPreventive medicineAssociations of steps per day and step intensity with the risk of cancer: Findings from the Women's Health Accelerometry Collaboration cohort.PMC1133869975N92021D0000175N92021D0000275N92021D00003UM1 CA182913R01 HL04385175N92021D00004R01 HL130483R01 HL10506575N92021D00005P30 AG059299R01 CA227122RC1 HL099355R01 HL080467R01 CA047988U54 CA132379U54 CA132384R01 CA154647K01 CA234317T32 HL007055U01 CA182913Howard AGManson JELaCroix AZBuring JDi CEvenson KRMoore CCParada HCuthbertson CCShiroma EJLee IMMatthews CEWen FfalseAssociations of steps per day and step intensity with the risk of cancer: Findings from the Women's Health Accelerometry Collaboration cohort.<h4>Objective</h4>Accumulating more steps/day is associated with a lower risk of cancer mortality and composite cancer outcomes. However, less is known about the relationship of steps/day with the risk of multiple site-specific cancers.<h4>Methods</h4>This study included >22,000 women from the Women's Health Accelerometry Collaboration Cohort (2011-2022), comprised of women from the Women's Health Study and Women's Health Initiative Objective Physical Activity and Cardiovascular Health Study. Steps/day and step intensity were collected with accelerometry. Incident cancer cases and deaths were adjudicated. Stratified Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) of the associations of steps/day and step intensity with incident b2024-01-01T00:00:00Z2024 Sep2026-05-29T05:04:46.653Z2026-04-08T03:44:57.665ZS-EPMC113386993902974310.1016/j.ypmed.2024.108070