{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Gross RS"],"funding":["NIDA NIH HHS","NIAID NIH HHS","NHLBI NIH HHS"],"pubmed_abstract":["<h4>Importance</h4>Most research to understand postacute sequelae of SARS-CoV-2 infection (PASC), or long COVID, has focused on adults, with less known about this complex condition in children. Research is needed to characterize pediatric PASC to enable studies of underlying mechanisms that will guide future treatment.<h4>Objective</h4>To identify the most common prolonged symptoms experienced by children (aged 6 to 17 years) after SARS-CoV-2 infection, how these symptoms differ by age (school-age [6-11 years] vs adolescents [12-17 years]), how they cluster into distinct phenotypes, and what symptoms in combination could be used as an empirically derived index to assist researchers to study the likely presence of PASC.<h4>Design, setting, and participants</h4>Multicenter longitudinal obser"],"journal":["JAMA"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11339705"],"repository":["biostudies-literature"],"pubmed_title":["Characterizing Long COVID in Children and Adolescents."],"pmcid":["PMC11339705"],"funding_grant_id":["R01 HL162373","U01 DA041120","U01 DA041156","U24 DA041147","OT2 HL161841","K23 AI159518"],"pubmed_authors":["Artis D","Caldera 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Adolescents.","description":"<h4>Importance</h4>Most research to understand postacute sequelae of SARS-CoV-2 infection (PASC), or long COVID, has focused on adults, with less known about this complex condition in children. Research is needed to characterize pediatric PASC to enable studies of underlying mechanisms that will guide future treatment.<h4>Objective</h4>To identify the most common prolonged symptoms experienced by children (aged 6 to 17 years) after SARS-CoV-2 infection, how these symptoms differ by age (school-age [6-11 years] vs adolescents [12-17 years]), how they cluster into distinct phenotypes, and what symptoms in combination could be used as an empirically derived index to assist researchers to study the likely presence of PASC.<h4>Design, setting, and participants</h4>Multicenter longitudinal obser","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Aug","modification":"2025-04-03T23:56:08.574Z","creation":"2025-04-03T23:56:08.574Z"},"accession":"S-EPMC11339705","cross_references":{"pubmed":["39196964"],"doi":["10.1001/jama.2024.12747"]}}