{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Yechezkel M"],"funding":["European Research Council","Koret Foundation","Israel Science Foundation (ISF)"],"pagination":["169"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11344792"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["4(1)"],"pubmed_abstract":["<h4>Background</h4>Public reluctance to receive COVID-19 vaccination is associated with safety concerns. By contrast, the seasonal influenza vaccine has been administered for decades with a solid safety record and a high level of public acceptance. We compare the safety profile of the BNT162b2 COVID-19 booster vaccine to that of the seasonal influenza vaccine.<h4>Methods</h4>We study a prospective cohort of 5079 participants in Israel and a retrospective cohort of 250,000 members of MHS selected randomly. We examine reactions to BNT162b2 mRNA COVID-19 booster and to influenza vaccinations. All prospective cohort participants wore a smartwatch and completed a daily digital questionnaire. We compare pre-vaccination and post-vaccination smartwatch heart-rate data, and a stress measure based o"],"journal":["Communications medicine"],"pubmed_title":["Comparison of physiological and clinical reactions to COVID-19 and influenza vaccination."],"pmcid":["PMC11344792"],"funding_grant_id":["gift for Smart Cities and Digital Living","3409/19","#949850"],"pubmed_authors":["Shmueli E","Qian G","Brandeau ML","Levi Y","Davidovitch N","Yamin D","Yechezkel M"],"additional_accession":[]},"is_claimable":false,"name":"Comparison of physiological and clinical reactions to COVID-19 and influenza vaccination.","description":"<h4>Background</h4>Public reluctance to receive COVID-19 vaccination is associated with safety concerns. By contrast, the seasonal influenza vaccine has been administered for decades with a solid safety record and a high level of public acceptance. We compare the safety profile of the BNT162b2 COVID-19 booster vaccine to that of the seasonal influenza vaccine.<h4>Methods</h4>We study a prospective cohort of 5079 participants in Israel and a retrospective cohort of 250,000 members of MHS selected randomly. We examine reactions to BNT162b2 mRNA COVID-19 booster and to influenza vaccinations. All prospective cohort participants wore a smartwatch and completed a daily digital questionnaire. We compare pre-vaccination and post-vaccination smartwatch heart-rate data, and a stress measure based o","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Aug","modification":"2025-04-18T16:55:09.757Z","creation":"2025-04-07T04:24:43.776Z"},"accession":"S-EPMC11344792","cross_references":{"pubmed":["39181950"],"doi":["10.1038/s43856-024-00588-7"]}}