{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Abrar A"],"funding":["Chan Zuckerberg Foundation","Bill and Melinda Gates Foundation","Resolve to Save Lives","Bloomberg Philanthropies"],"pagination":["1090-1098"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11347191"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["110(17)"],"pubmed_abstract":["<h4>Background</h4>The World Health Organization (WHO) promotes the HEARTS technical package for improving hypertension control worldwide, but its effectiveness has not been rigorously evaluated.<h4>Objective</h4>To compare hypertension outcomes in clinics implementing HEARTS versus clinics continuing usual hypertension care in rural Bangladesh.<h4>Methods</h4>A matched-pair cluster quasi-experimental trial in Upazila Health Complexes (UHCs; primary healthcare facilities) was conducted in rural Bangladesh. A total of 3935 patients (mean age 52.3 years, 70.5% female) with uncontrolled hypertension (blood pressure (BP) ≥140/90 mm Hg regardless of treatment history) were enrolled: 1950 patients from 7 HEARTS UHCs and 1985 patients from 7 matched usual care UHCs. The primary outcome was systol"],"journal":["Heart (British Cardiac Society)"],"pubmed_title":["Evaluation of the World Health Organization-HEARTS hypertension control package in Bangladesh: a quasi-experimental trial."],"pmcid":["PMC11347191"],"funding_grant_id":["OPP1175906"],"pubmed_authors":["Gupta R","Al Mamun MA","Burka D","Abrar A","Hu X","Moran AE","Malik F","Sultana S","Matsushita K","Bhuiyan MR","Farrell M","Banigbe B","Appel L","Choudhury SR","Amin MR","Zhao D","Jubayer S","Akhtar J","Noor Nabi Sayem M","Alim A"],"additional_accession":[]},"is_claimable":false,"name":"Evaluation of the World Health Organization-HEARTS hypertension control package in Bangladesh: a quasi-experimental trial.","description":"<h4>Background</h4>The World Health Organization (WHO) promotes the HEARTS technical package for improving hypertension control worldwide, but its effectiveness has not been rigorously evaluated.<h4>Objective</h4>To compare hypertension outcomes in clinics implementing HEARTS versus clinics continuing usual hypertension care in rural Bangladesh.<h4>Methods</h4>A matched-pair cluster quasi-experimental trial in Upazila Health Complexes (UHCs; primary healthcare facilities) was conducted in rural Bangladesh. A total of 3935 patients (mean age 52.3 years, 70.5% female) with uncontrolled hypertension (blood pressure (BP) ≥140/90 mm Hg regardless of treatment history) were enrolled: 1950 patients from 7 HEARTS UHCs and 1985 patients from 7 matched usual care UHCs. The primary outcome was systol","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Aug","modification":"2026-06-14T05:20:50.901Z","creation":"2026-06-14T03:08:47.186Z"},"accession":"S-EPMC11347191","cross_references":{"pubmed":["39019496"],"doi":["10.1136/heartjnl-2024-324253"]}}