biostudies-literatureAbrar AChan Zuckerberg FoundationBill and Melinda Gates FoundationResolve to Save LivesBloomberg Philanthropies1090-1098https://www.ebi.ac.uk/biostudies/studies/S-EPMC11347191biostudies-literatureUnknown110(17)<h4>Background</h4>The World Health Organization (WHO) promotes the HEARTS technical package for improving hypertension control worldwide, but its effectiveness has not been rigorously evaluated.<h4>Objective</h4>To compare hypertension outcomes in clinics implementing HEARTS versus clinics continuing usual hypertension care in rural Bangladesh.<h4>Methods</h4>A matched-pair cluster quasi-experimental trial in Upazila Health Complexes (UHCs; primary healthcare facilities) was conducted in rural Bangladesh. A total of 3935 patients (mean age 52.3 years, 70.5% female) with uncontrolled hypertension (blood pressure (BP) ≥140/90 mm Hg regardless of treatment history) were enrolled: 1950 patients from 7 HEARTS UHCs and 1985 patients from 7 matched usual care UHCs. The primary outcome was systolHeart (British Cardiac Society)Evaluation of the World Health Organization-HEARTS hypertension control package in Bangladesh: a quasi-experimental trial.PMC11347191OPP1175906Gupta RAl Mamun MABurka DAbrar AHu XMoran AEMalik FSultana SMatsushita KBhuiyan MRFarrell MBanigbe BAppel LChoudhury SRAmin MRZhao DJubayer SAkhtar JNoor Nabi Sayem MAlim AfalseEvaluation of the World Health Organization-HEARTS hypertension control package in Bangladesh: a quasi-experimental trial.<h4>Background</h4>The World Health Organization (WHO) promotes the HEARTS technical package for improving hypertension control worldwide, but its effectiveness has not been rigorously evaluated.<h4>Objective</h4>To compare hypertension outcomes in clinics implementing HEARTS versus clinics continuing usual hypertension care in rural Bangladesh.<h4>Methods</h4>A matched-pair cluster quasi-experimental trial in Upazila Health Complexes (UHCs; primary healthcare facilities) was conducted in rural Bangladesh. A total of 3935 patients (mean age 52.3 years, 70.5% female) with uncontrolled hypertension (blood pressure (BP) ≥140/90 mm Hg regardless of treatment history) were enrolled: 1950 patients from 7 HEARTS UHCs and 1985 patients from 7 matched usual care UHCs. The primary outcome was systol2024-01-01T00:00:00Z2024 Aug2026-06-14T05:20:50.901Z2026-06-14T03:08:47.186ZS-EPMC113471913901949610.1136/heartjnl-2024-324253