biostudies-literatureManoharan MKSEED Co., Ltd, Japan1292-1298https://www.ebi.ac.uk/biostudies/studies/S-EPMC11347265biostudies-literatureUnknown108(9)<h4>Purpose</h4>To determine the efficacy of extended depth of focus (EDOF) contact lenses for controlling myopia progression in children through a 1-year randomised clinical trial.<h4>Methods</h4>A total of 104 children aged 7-15 years, with spherical equivalent refraction ≤-0.50 D, were randomly assigned to wear SEED 1 dayPure EDOF Mid contact lenses (n=48) or single vision spectacle lenses (n=56). Cycloplegic refraction with Shin-Nippon open field autorefractor and axial length with Lenstar LS 900 was determined at the baseline and 12-month visits. The compliance, visual discomfort and dryness questionnaires were administered during the final visit.<h4>Results</h4>Sixty-nine children (control: n=38; treatment: 31) completed the 12-month follow-up visit, with no difference in baseline chThe British journal of ophthalmologyRandomised clinical trial of extended depth of focus lenses for controlling myopia progression: Outcomes from SEED LVPEI Indian Myopia Study.PMC11347265N/AManoharan MKVerkicharla PKfalseRandomised clinical trial of extended depth of focus lenses for controlling myopia progression: Outcomes from SEED LVPEI Indian Myopia Study.<h4>Purpose</h4>To determine the efficacy of extended depth of focus (EDOF) contact lenses for controlling myopia progression in children through a 1-year randomised clinical trial.<h4>Methods</h4>A total of 104 children aged 7-15 years, with spherical equivalent refraction ≤-0.50 D, were randomly assigned to wear SEED 1 dayPure EDOF Mid contact lenses (n=48) or single vision spectacle lenses (n=56). Cycloplegic refraction with Shin-Nippon open field autorefractor and axial length with Lenstar LS 900 was determined at the baseline and 12-month visits. The compliance, visual discomfort and dryness questionnaires were administered during the final visit.<h4>Results</h4>Sixty-nine children (control: n=38; treatment: 31) completed the 12-month follow-up visit, with no difference in baseline ch2024-01-01T00:00:00Z2024 Aug2026-06-14T05:20:53.728Z2026-06-14T03:08:48.711ZS-EPMC113472653860462210.1136/bjo-2023-323651