biostudies-literatureLi SChongqing Science and Health Joint Projectzhongjun WuChongqing Research Performance Incentive and Guidance ProjectZuotian HuangChongqing Technology Innovation and Application Development Key Project551https://www.ebi.ac.uk/biostudies/studies/S-EPMC11358929biostudies-literatureUnknown12(8)<h4>Background</h4>Ethylene oxide, a reactive epoxy compound, has been widely used in various industries for many years. However, evidence of the combined toxic effects of ethylene oxide exposure on the liver is still lacking.<h4>Methods</h4>We analyzed the merged data from the National Health and Nutrition Examination Survey (NHANES) from 2013 to 2016. Ultimately, 4141 adults aged 18 and over were selected as the sample. We used linear regression to explore the association between blood ethylene oxide and LFT indicators.<h4>Results</h4>The weighted linear regression model showed that HbEO is positively correlated with ALP (<i>β</i> = 2.61, 95% CI 1.97, 3.24, <i>p</i> < 0.0001), GGT (<i>β</i> = 5.75, 95% CI 4.46, 7/05, <i>p</i> < 0.0001), ALT (<i>β</i> = 0.50, 95% CI 0.09, 0.90, <i>p</i> =ToxicsAssociations between Ethylene Oxide Exposure and Liver Function in the US Adult Population.PMC11358929cstc2021jscx-gksbX0060cstc2022jxjl1200322024GGXM005Wu ZLiu YLi SPeng DHuang ZLei DZong KLi KWang JfalseAssociations between Ethylene Oxide Exposure and Liver Function in the US Adult Population.<h4>Background</h4>Ethylene oxide, a reactive epoxy compound, has been widely used in various industries for many years. However, evidence of the combined toxic effects of ethylene oxide exposure on the liver is still lacking.<h4>Methods</h4>We analyzed the merged data from the National Health and Nutrition Examination Survey (NHANES) from 2013 to 2016. Ultimately, 4141 adults aged 18 and over were selected as the sample. We used linear regression to explore the association between blood ethylene oxide and LFT indicators.<h4>Results</h4>The weighted linear regression model showed that HbEO is positively correlated with ALP (<i>β</i> = 2.61, 95% CI 1.97, 3.24, <i>p</i> < 0.0001), GGT (<i>β</i> = 5.75, 95% CI 4.46, 7/05, <i>p</i> < 0.0001), ALT (<i>β</i> = 0.50, 95% CI 0.09, 0.90, <i>p</i> =2024-01-01T00:00:00Z2024 Jul2026-04-07T21:12:32.281Z2025-04-05T12:30:57.922ZS-EPMC113589293919565310.3390/toxics12080551