{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Tian F"],"funding":["Gordon and Betty Moore Foundation Investigator Award","National Science Foundation"],"pagination":["159"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11360552"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(1)"],"pubmed_abstract":["<h4>Background</h4>Prokaryotic microbes have impacted marine biogeochemical cycles for billions of years. Viruses also impact these cycles, through lysis, horizontal gene transfer, and encoding and expressing genes that contribute to metabolic reprogramming of prokaryotic cells. While this impact is difficult to quantify in nature, we hypothesized that it can be examined by surveying virus-encoded auxiliary metabolic genes (AMGs) and assessing their ecological context.<h4>Results</h4>We systematically developed a global ocean AMG catalog by integrating previously described and newly identified AMGs and then placed this catalog into ecological and metabolic contexts relevant to ocean biogeochemistry. From 7.6 terabases of Tara Oceans paired prokaryote- and virus-enriched metagenomic sequenc"],"journal":["Microbiome"],"pubmed_title":["Prokaryotic-virus-encoded auxiliary metabolic genes throughout the global oceans."],"pmcid":["PMC11360552"],"funding_grant_id":["ABI#1759874, ABI#2149505, OCE#1536989, OCE#1829831, and OCE#2019589","#3790"],"pubmed_authors":["Tian F","Gazitua MC","Howard-Varona C","Smith G","Dominguez-Huerta G","Gittrich MR","Cronin DR","Eveillard D","Bolduc B","Zablocki O","Hallam SJ","Wainaina JM","Sullivan MB"],"additional_accession":[]},"is_claimable":false,"name":"Prokaryotic-virus-encoded auxiliary metabolic genes throughout the global oceans.","description":"<h4>Background</h4>Prokaryotic microbes have impacted marine biogeochemical cycles for billions of years. Viruses also impact these cycles, through lysis, horizontal gene transfer, and encoding and expressing genes that contribute to metabolic reprogramming of prokaryotic cells. While this impact is difficult to quantify in nature, we hypothesized that it can be examined by surveying virus-encoded auxiliary metabolic genes (AMGs) and assessing their ecological context.<h4>Results</h4>We systematically developed a global ocean AMG catalog by integrating previously described and newly identified AMGs and then placed this catalog into ecological and metabolic contexts relevant to ocean biogeochemistry. From 7.6 terabases of Tara Oceans paired prokaryote- and virus-enriched metagenomic sequenc","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Aug","modification":"2025-04-04T10:38:59.519Z","creation":"2025-04-04T10:38:59.519Z"},"accession":"S-EPMC11360552","cross_references":{"pubmed":["39198891"],"doi":["10.1186/s40168-024-01876-z"]}}