{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Anesi GL"],"funding":["NHLBI NIH HHS"],"pagination":["100005"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11360720"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["1(1)"],"pubmed_abstract":["<h4>Background</h4>Hospital adaptation and resiliency, required during public health emergencies to optimize outcomes, are understudied especially in resource-limited settings.<h4>Research question</h4>What are the prepandemic and pandemic critical illness outcomes in a resource-limited setting and in the context of capacity strain?<h4>Study design and methods</h4>We performed a retrospective cohort study among patients admitted to ICUs at two public hospitals in the KwaZulu-Natal Department of Health in South Africa preceding and during the COVID-19 pandemic (2017-2022). We used multivariate logistic regression to analyze the association between three patient cohorts (prepandemic non-COVID-19, pandemic non-COVID-19, and pandemic COVID-19) and ICU capacity strain and the primary outcome of"],"journal":["CHEST critical care"],"pubmed_title":["ICU Mortality Across Prepandemic and Pandemic Cohorts in a Resource-Limited Setting: A Critical Care Resiliency Analysis From South Africa."],"pmcid":["PMC11360720"],"funding_grant_id":["K23 HL161353"],"pubmed_authors":["Hyman R","Wise RD","Savarimuthu SM","Smith MTD","Ramkillawan A","Invernizzi J","Anesi GL","Eddey C"],"additional_accession":[]},"is_claimable":false,"name":"ICU Mortality Across Prepandemic and Pandemic Cohorts in a Resource-Limited Setting: A Critical Care Resiliency Analysis From South Africa.","description":"<h4>Background</h4>Hospital adaptation and resiliency, required during public health emergencies to optimize outcomes, are understudied especially in resource-limited settings.<h4>Research question</h4>What are the prepandemic and pandemic critical illness outcomes in a resource-limited setting and in the context of capacity strain?<h4>Study design and methods</h4>We performed a retrospective cohort study among patients admitted to ICUs at two public hospitals in the KwaZulu-Natal Department of Health in South Africa preceding and during the COVID-19 pandemic (2017-2022). We used multivariate logistic regression to analyze the association between three patient cohorts (prepandemic non-COVID-19, pandemic non-COVID-19, and pandemic COVID-19) and ICU capacity strain and the primary outcome of","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jun","modification":"2025-04-26T14:27:46.136Z","creation":"2024-11-09T17:34:54.056Z"},"accession":"S-EPMC11360720","cross_references":{"pubmed":["39211576"],"doi":["10.1016/j.chstcc.2023.100005"]}}