{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["22(1)"],"submitter":["Zheng Y"],"pubmed_abstract":["<h4>Background</h4>Obesity and metabolic syndrome (MetS) have become urgent worldwide health problems, predisposing patients to unfavorable myocardial status and thyroid dysfunction. Low-carbohydrate diet (LCD) and time-restricted eating (TRE) have been confirmed to be effective methods for weight management and improving MetS, but their effects on the myocardium and thyroid are unclear.<h4>Methods</h4>We conducted a secondary analysis in a randomized clinical diet-induced weight-loss trial. Participants (N = 169) diagnosed with MetS were randomized to the LCD group, the 8 h TRE group, or the combination of the LCD and TRE group for 3 months. Myocardial enzymes and thyroid function were tested before and after the intervention. Pearson's or Spearman's correlation was assessed between funct"],"journal":["BMC medicine"],"pagination":["362"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11373390"],"repository":["biostudies-literature"],"pubmed_title":["Time-restricted eating with or without a low-carbohydrate diet improved myocardial status and thyroid function in individuals with metabolic syndrome: secondary analysis of a randomized clinical trial."],"pmcid":["PMC11373390"],"pubmed_authors":["Zheng Y","Yang J","Liu M","He M","Lin X","Qiang W","Zhang M","Wang J","Zhou X","Li M","Shi B","Chen Z","Guo H","Sui J","Wang Y","Liang Q"],"additional_accession":[]},"is_claimable":false,"name":"Time-restricted eating with or without a low-carbohydrate diet improved myocardial status and thyroid function in individuals with metabolic syndrome: secondary analysis of a randomized clinical trial.","description":"<h4>Background</h4>Obesity and metabolic syndrome (MetS) have become urgent worldwide health problems, predisposing patients to unfavorable myocardial status and thyroid dysfunction. Low-carbohydrate diet (LCD) and time-restricted eating (TRE) have been confirmed to be effective methods for weight management and improving MetS, but their effects on the myocardium and thyroid are unclear.<h4>Methods</h4>We conducted a secondary analysis in a randomized clinical diet-induced weight-loss trial. Participants (N = 169) diagnosed with MetS were randomized to the LCD group, the 8 h TRE group, or the combination of the LCD and TRE group for 3 months. Myocardial enzymes and thyroid function were tested before and after the intervention. Pearson's or Spearman's correlation was assessed between funct","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Sep","modification":"2026-07-15T11:00:13.88Z","creation":"2026-07-03T03:15:51.478Z"},"accession":"S-EPMC11373390","cross_references":{"pubmed":["39227921"],"doi":["10.1186/s12916-024-03595-6"]}}