{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Chow KW"],"funding":["NCATS NIH HHS"],"pagination":["2389-2397"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11380462"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["68(6)"],"pubmed_abstract":["<h4>Background</h4>Hepatic encephalopathy (HE) is a major cause of mortality and morbidity in patients with cirrhosis. Lactulose non-adherence is one of the most frequently reported precipitants of hospital admission for HE.<h4>Aims</h4>We aimed to identify which factors contribute most to lactulose non-adherence and propose strategies to promote greater adherence and utilization of lactulose.<h4>Methods</h4>Participants in this study consisted of patients with cirrhosis who were taking lactulose for prevention of HE. Subjects were administered the Morisky Adherence Scale 8 (MAS-8) and a customized 16-question survey that assessed barriers to lactulose adherence. Results from the MAS-8 were used to stratify subjects into \"adherent\" and \"non-adherent\" groups. Survey responses were compared "],"journal":["Digestive diseases and sciences"],"pubmed_title":["Barriers to Lactulose Adherence in Patients with Cirrhosis and Hepatic Encephalopathy."],"pmcid":["PMC11380462"],"funding_grant_id":["UL1 TR001881"],"pubmed_authors":["Ibrahim BM","Chen KT","Dang L","Chow KW","Dang A","Saab S","Jackson NJ","Yum JJ"],"additional_accession":[]},"is_claimable":false,"name":"Barriers to Lactulose Adherence in Patients with Cirrhosis and Hepatic Encephalopathy.","description":"<h4>Background</h4>Hepatic encephalopathy (HE) is a major cause of mortality and morbidity in patients with cirrhosis. Lactulose non-adherence is one of the most frequently reported precipitants of hospital admission for HE.<h4>Aims</h4>We aimed to identify which factors contribute most to lactulose non-adherence and propose strategies to promote greater adherence and utilization of lactulose.<h4>Methods</h4>Participants in this study consisted of patients with cirrhosis who were taking lactulose for prevention of HE. Subjects were administered the Morisky Adherence Scale 8 (MAS-8) and a customized 16-question survey that assessed barriers to lactulose adherence. Results from the MAS-8 were used to stratify subjects into \"adherent\" and \"non-adherent\" groups. Survey responses were compared ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jun","modification":"2025-04-05T14:38:36.871Z","creation":"2025-04-05T14:38:36.871Z"},"accession":"S-EPMC11380462","cross_references":{"pubmed":["37119376"],"doi":["10.1007/s10620-023-07935-z"]}}