{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kong Z"],"funding":["Liaoning Talent Development Program","Science and Technology Research Project of the Department of Education of Liaoning Province","Shenyang Youth Science and Technology Innovation Talent Support Program","China Postdoctoral Science Foundation","National Natural Science Foundation of China","Chinese Association of Traditional Chinese Medicine Youth Talent Support Program","Innovation Project of Science and Technology of China Academy of Chinese Medical Sciences"],"pagination":["2396567"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11389646"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["56(1)"],"pubmed_abstract":["<h4>Objective</h4>To develop a comprehensive framework for selecting outcomes in evaluating the clinical efficacy of Chinese herbal injections and to scientifically select outcomes for the clinical randomized controlled trial (RCT) of Tan-Re-Qing injection intervening AECOPD.<h4>Methods</h4>A comprehensive literature review and consensus methods, including focus groups and Delphi surveys, were utilized.<h4>Results</h4>Literature analysis identified 513 publications, encompassing regulatory guidance, guidelines, expert consensus, and RCTs. Initial dimensions include clinical efficacy, safety, and health economics. Primary outcomes should align with study objectives. Recommended evaluation domains include death, treatment outcome, future impact, quality of life, and safety. Commonly recommen"],"journal":["Annals of medicine"],"pubmed_title":["Methodology for the selection and evaluation of outcomes for Chinese herbal injection in acute exacerbation of chronic obstructive pulmonary disease (AECOPD): a comprehensive study."],"pmcid":["PMC11389646"],"funding_grant_id":["CI2021A05501","L201713","81803978","2022–2024","XLYC2203035","RC200104","2021M703618"],"pubmed_authors":["Zhang TW","Lu Y","Yang SH","Kong Z","Zhao H","Hao XW"],"additional_accession":[]},"is_claimable":false,"name":"Methodology for the selection and evaluation of outcomes for Chinese herbal injection in acute exacerbation of chronic obstructive pulmonary disease (AECOPD): a comprehensive study.","description":"<h4>Objective</h4>To develop a comprehensive framework for selecting outcomes in evaluating the clinical efficacy of Chinese herbal injections and to scientifically select outcomes for the clinical randomized controlled trial (RCT) of Tan-Re-Qing injection intervening AECOPD.<h4>Methods</h4>A comprehensive literature review and consensus methods, including focus groups and Delphi surveys, were utilized.<h4>Results</h4>Literature analysis identified 513 publications, encompassing regulatory guidance, guidelines, expert consensus, and RCTs. Initial dimensions include clinical efficacy, safety, and health economics. Primary outcomes should align with study objectives. Recommended evaluation domains include death, treatment outcome, future impact, quality of life, and safety. Commonly recommen","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Dec","modification":"2026-06-01T10:07:42.138Z","creation":"2025-04-04T09:49:11.183Z"},"accession":"S-EPMC11389646","cross_references":{"pubmed":["39253851"],"doi":["10.1080/07853890.2024.2396567"]}}