{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Deprez A"],"funding":["Fonds de recherche du Québec – Nature et Technologies","Canadian Institutes of Health Research","Fonds de recherche du Québec - Nature et Technologies","CIHR"],"pagination":["21457"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11399148"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(1)"],"pubmed_abstract":["Prematurity is associated with lower exercise capacity, which relies on the integrity of the cardiovascular, pulmonary, and skeletal muscle systems. Our animal model mimicking prematurity-associated conditions showed altered muscle composition and atrophy in adulthood. This study aimed to compare muscle composition and strength in adults born preterm versus full-term controls. This observational cohort study recruited 55 adults born preterm, ≤ 29 weeks' of gestation and 53 full-term controls who underwent musculoskeletal ultrasound imaging to assess morphology of the rectus femoris at rest and during a maximal voluntary contraction. Maximal voluntary contraction of the hands and legs were measured by manual dynamometry. In adults born preterm, there was lower muscle strength (handgrip: - 4"],"journal":["Scientific reports"],"pubmed_title":["Adults born preterm have lower peripheral skeletal muscle area and strength."],"pmcid":["PMC11399148"],"funding_grant_id":["275929","PJT-174993","PJT-173404"],"pubmed_authors":["Mathieu ME","Dumont NA","Nuyt AM","Deprez A","El-Jalbout R","Gagnon DH","Luu TM","Kugathasan TA","Cloutier A","Gagnon Hamelin A"],"additional_accession":[]},"is_claimable":false,"name":"Adults born preterm have lower peripheral skeletal muscle area and strength.","description":"Prematurity is associated with lower exercise capacity, which relies on the integrity of the cardiovascular, pulmonary, and skeletal muscle systems. Our animal model mimicking prematurity-associated conditions showed altered muscle composition and atrophy in adulthood. This study aimed to compare muscle composition and strength in adults born preterm versus full-term controls. This observational cohort study recruited 55 adults born preterm, ≤ 29 weeks' of gestation and 53 full-term controls who underwent musculoskeletal ultrasound imaging to assess morphology of the rectus femoris at rest and during a maximal voluntary contraction. Maximal voluntary contraction of the hands and legs were measured by manual dynamometry. In adults born preterm, there was lower muscle strength (handgrip: - 4","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Sep","modification":"2026-06-01T09:11:44.857Z","creation":"2025-04-04T02:54:33.579Z"},"accession":"S-EPMC11399148","cross_references":{"pubmed":["39271745"],"doi":["10.1038/s41598-024-72533-6"]}}