biostudies-literatureUnknown34(10)Schmidt VF<h4>Objectives</h4>To evaluate the safety and clinical outcome of bleomycin electrosclerotherapy (BEST) for treating extracranial slow-flow malformations.<h4>Methods</h4>In this retrospective investigation of a multicenter cohort presenting symptomatic slow-flow malformations, patient records were analyzed with respect to procedural details and complications. A treatment-specific, patient-reported questionnaire was additionally evaluated, obtained 3-12 months after the last treatment, to assess the subjective outcomes, including mobility, aesthetic aspects, and pain, as well as the occurrence of postprocedural skin hyperpigmentation. All outcome parameters were compared according to patients' age.<h4>Results</h4>Overall, 325 BEST treatments were performed in 233 patients after intralesionaEuropean radiology6425-6434https://www.ebi.ac.uk/biostudies/studies/S-EPMC11399160biostudies-literatureOutcome of bleomycin electrosclerotherapy of slow-flow malformations in adults and children.PMC11399160Sint AOcal ORicke JWildgruber MMansour NWohlgemuth WASchmidt VFGoldann CHengst Svon der Heydt SMeyer LObereisenbuchner FUmutlu MRCangir OSeidensticker MRudolph JBrill RHaberle BPuhr-Westerheide DWaner MfalseOutcome of bleomycin electrosclerotherapy of slow-flow malformations in adults and children.<h4>Objectives</h4>To evaluate the safety and clinical outcome of bleomycin electrosclerotherapy (BEST) for treating extracranial slow-flow malformations.<h4>Methods</h4>In this retrospective investigation of a multicenter cohort presenting symptomatic slow-flow malformations, patient records were analyzed with respect to procedural details and complications. A treatment-specific, patient-reported questionnaire was additionally evaluated, obtained 3-12 months after the last treatment, to assess the subjective outcomes, including mobility, aesthetic aspects, and pain, as well as the occurrence of postprocedural skin hyperpigmentation. All outcome parameters were compared according to patients' age.<h4>Results</h4>Overall, 325 BEST treatments were performed in 233 patients after intralesiona2024-01-01T00:00:00Z2024 Oct2026-06-02T23:38:24.902Z2025-04-05T18:42:28.02ZS-EPMC113991603862728710.1007/s00330-024-10723-6