{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Tao Z"],"funding":["State Key Laboratory of Hybrid Rice"],"pagination":["8107"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11405696"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(1)"],"pubmed_abstract":["Brown planthopper (BPH) is the most destructive insect pest of rice. Drought is the most detrimental environmental stress. BPH infestation causes adaxial leaf-rolling and bulliform cells (BCs) shrinkage similar to drought. The BC-related abaxially curled leaf1 (ACL1) gene negatively regulates BPH resistance and drought tolerance, with decreased cuticular wax in the gain-of-function mutant ACL1-D. ACL1 shows an epidermis-specific expression. The TurboID system and multiple biochemical assays reveal that ACL1 interacts with the epidermal-characteristic rice outermost cell-specific (ROC) proteins. ROC4 and ROC5 positively regulate BPH resistance and drought tolerance through modulating cuticular wax and BCs, respectively. Overexpression of ROC4 and ROC5 both rescue ACL1-D mutant in various re"],"journal":["Nature communications"],"pubmed_title":["ACL1-ROC4/5 complex reveals a common mechanism in rice response to brown planthopper infestation and drought."],"pmcid":["PMC11405696"],"funding_grant_id":["KF201805"],"pubmed_authors":["Liu X","Tao Z","Li H","Li D","Zhu L","Sun B","Hu W","Wang S","Miao X","Shi Z"],"additional_accession":[]},"is_claimable":false,"name":"ACL1-ROC4/5 complex reveals a common mechanism in rice response to brown planthopper infestation and drought.","description":"Brown planthopper (BPH) is the most destructive insect pest of rice. Drought is the most detrimental environmental stress. BPH infestation causes adaxial leaf-rolling and bulliform cells (BCs) shrinkage similar to drought. The BC-related abaxially curled leaf1 (ACL1) gene negatively regulates BPH resistance and drought tolerance, with decreased cuticular wax in the gain-of-function mutant ACL1-D. ACL1 shows an epidermis-specific expression. The TurboID system and multiple biochemical assays reveal that ACL1 interacts with the epidermal-characteristic rice outermost cell-specific (ROC) proteins. ROC4 and ROC5 positively regulate BPH resistance and drought tolerance through modulating cuticular wax and BCs, respectively. Overexpression of ROC4 and ROC5 both rescue ACL1-D mutant in various re","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Sep","modification":"2026-06-03T21:18:14.436Z","creation":"2025-04-05T18:45:35.843Z"},"accession":"S-EPMC11405696","cross_references":{"pubmed":["39285171"],"doi":["10.1038/s41467-024-52436-w"]}}