{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["31"],"submitter":["Nguyen CTT"],"pubmed_abstract":["<h4>Objectives</h4>The associations between the neutrophil-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) with the responses of non-small cell lung cancer (NSCLC) patients receiving immune checkpoint inhibitors (ICI) and the NLR/PLR predictive potential were evaluated via meta-analysis.<h4>Methods</h4>A systematic review was conducted using the PubMed, Embase, and The Cochrane Library databases until October 2021. The relationship between NLR/PLR and overall survival (OS) and progression-free survival (PFS) was evaluated using pooled hazard ratios (HR). The relationship between NLR/PLR and overall response rate (ORR) and disease control rate (DCR) was assessed via pooled odds ratios (OR). Heterogeneity between studies, publication bias, subgroup and sensitivity analyses, tri"],"journal":["Cancer control : journal of the Moffitt Cancer Center"],"pagination":["10732748241285474"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11406641"],"repository":["biostudies-literature"],"pubmed_title":["Predictability of Neutrophile to Lymphocyte Ratio and Platelet to Lymphocyte Ratio on the Effectiveness of Immune Checkpoint Inhibitors in Non-small Cell Lung Cancer patients: A Meta-Analysis."],"pmcid":["PMC11406641"],"pubmed_authors":["Nguyen CTT","Huong PT","Van TNK"],"additional_accession":[]},"is_claimable":false,"name":"Predictability of Neutrophile to Lymphocyte Ratio and Platelet to Lymphocyte Ratio on the Effectiveness of Immune Checkpoint Inhibitors in Non-small Cell Lung Cancer patients: A Meta-Analysis.","description":"<h4>Objectives</h4>The associations between the neutrophil-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) with the responses of non-small cell lung cancer (NSCLC) patients receiving immune checkpoint inhibitors (ICI) and the NLR/PLR predictive potential were evaluated via meta-analysis.<h4>Methods</h4>A systematic review was conducted using the PubMed, Embase, and The Cochrane Library databases until October 2021. The relationship between NLR/PLR and overall survival (OS) and progression-free survival (PFS) was evaluated using pooled hazard ratios (HR). The relationship between NLR/PLR and overall response rate (ORR) and disease control rate (DCR) was assessed via pooled odds ratios (OR). Heterogeneity between studies, publication bias, subgroup and sensitivity analyses, tri","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Jan-Dec","modification":"2026-06-03T23:42:53.631Z","creation":"2025-04-04T11:33:53.851Z"},"accession":"S-EPMC11406641","cross_references":{"pubmed":["39285591"],"doi":["10.1177/10732748241285474"]}}