{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["6"],"submitter":["Willemse BW"],"pubmed_abstract":["<h4>Background</h4>Inflammation in the airways and lung parenchyma underlies fixed airway obstruction in chronic obstructive pulmonary disease. The exact role of smoking as promoting factor of inflammation in chronic obstructive pulmonary disease is not clear, partly because studies often do not distinguish between current and ex-smokers.<h4>Methods</h4>We investigated airway inflammation in sputum and bronchial biopsies of 34 smokers with chronic obstructive pulmonary disease (9 Global initiative for Chronic Obstructive Lung Disease stage 0, 9 stage I, 10 stage II and 6 stage III) and 26 asymptomatic smokers, and its relationship with past and present smoking habits and airway obstruction.<h4>Results</h4>Neutrophil percentage, interleukin-8 and eosinophilic-cationic-protein levels in sput"],"journal":["Respiratory research"],"pagination":["38"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC1140754"],"repository":["biostudies-literature"],"pubmed_title":["Association of current smoking with airway inflammation in chronic obstructive pulmonary disease and asymptomatic smokers."],"pmcid":["PMC1140754"],"pubmed_authors":["Willemse BW","ten Hacken NH","Postma DS","Rutgers B","Timens W"],"additional_accession":[]},"is_claimable":false,"name":"Association of current smoking with airway inflammation in chronic obstructive pulmonary disease and asymptomatic smokers.","description":"<h4>Background</h4>Inflammation in the airways and lung parenchyma underlies fixed airway obstruction in chronic obstructive pulmonary disease. The exact role of smoking as promoting factor of inflammation in chronic obstructive pulmonary disease is not clear, partly because studies often do not distinguish between current and ex-smokers.<h4>Methods</h4>We investigated airway inflammation in sputum and bronchial biopsies of 34 smokers with chronic obstructive pulmonary disease (9 Global initiative for Chronic Obstructive Lung Disease stage 0, 9 stage I, 10 stage II and 6 stage III) and 26 asymptomatic smokers, and its relationship with past and present smoking habits and airway obstruction.<h4>Results</h4>Neutrophil percentage, interleukin-8 and eosinophilic-cationic-protein levels in sput","dates":{"release":"2005-01-01T00:00:00Z","publication":"2005 Apr","modification":"2025-04-26T13:23:09.443Z","creation":"2019-03-27T01:08:57Z"},"accession":"S-EPMC1140754","cross_references":{"pubmed":["15850494"],"doi":["10.1186/1465-9921-6-38"]}}