{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14(1)"],"submitter":["Michel M"],"funding":["Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes"],"pubmed_abstract":["People with type 2 diabetes mellitus (T2DM) show a high prevalence of steatotic liver disease (SLD), and especially metabolic dysfunction-associated steatotic liver disease (MASLD), with liver fibrosis. Their health-related quality of life (HRQL) is affected by multiple in part overlapping factors and aggravated by metabolic and liver-related comorbidities, including liver fibrosis stage. The aim of this study was to investigate the effect size of advanced fibrosis (AF) on the HRQL in people with T2DM. A total of 149 individuals with T2DM treated at a primary care provider within the German disease management program (DMP) were included in the final analysis. Vibration-controlled transient elastography (VCTE) was used to non-invasively detect steatosis and AF. The EQ-5D-3L questionnaire wa"],"journal":["Scientific reports"],"pagination":["21650"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11408596"],"repository":["biostudies-literature"],"pubmed_title":["Impairment of health-related quality of life among people with type 2 diabetes and advanced liver fibrosis."],"pmcid":["PMC11408596"],"pubmed_authors":["Doll M","Funuyet-Salas J","Michel M","Labenz C","Schattenberg JM","Alqahtani SA","Galle PR","Armandi A"],"additional_accession":[]},"is_claimable":false,"name":"Impairment of health-related quality of life among people with type 2 diabetes and advanced liver fibrosis.","description":"People with type 2 diabetes mellitus (T2DM) show a high prevalence of steatotic liver disease (SLD), and especially metabolic dysfunction-associated steatotic liver disease (MASLD), with liver fibrosis. Their health-related quality of life (HRQL) is affected by multiple in part overlapping factors and aggravated by metabolic and liver-related comorbidities, including liver fibrosis stage. The aim of this study was to investigate the effect size of advanced fibrosis (AF) on the HRQL in people with T2DM. A total of 149 individuals with T2DM treated at a primary care provider within the German disease management program (DMP) were included in the final analysis. Vibration-controlled transient elastography (VCTE) was used to non-invasively detect steatosis and AF. The EQ-5D-3L questionnaire wa","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Sep","modification":"2025-04-20T00:39:50.428Z","creation":"2025-04-20T00:39:50.428Z"},"accession":"S-EPMC11408596","cross_references":{"pubmed":["39289410"],"doi":["10.1038/s41598-024-72105-8"]}}