{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14(40)"],"submitter":["Soliman AIA"],"funding":["Natural Sciences and Engineering Research Council of Canada","Assiut University","Zhejiang University","Canada Research Chairs"],"pubmed_abstract":["Knoevenagel condensation is a chemical reaction between aldehydes and active methylene-containing compounds in the presence of heterogeneous, basic homogenous organic or inorganic catalysts and solvent or neat systems. Herein, we introduced a new strategy for this synthesis by using the aqueous solution of cationic kraft lignin (CKL) as a catalyst. The CKL was synthesized through the reaction of kraft lignin (KL) with glycidyltrimethylammonium chloride (GTMAC) in a basic medium. The optimal reaction conditions for the Knoevenagel reaction were 5% catalyst load (weight of catalyst to the weight of benzaldehyde), water as the solvent, and at room temperature, which generated the products with a yield of 97%, illustrating that the CKL was an effective homogenous and green catalyst. The result"],"journal":["RSC advances"],"pagination":["29595-29605"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11409447"],"repository":["biostudies-literature"],"pubmed_title":["Cationic lignin as an efficient and sustainable homogenous catalyst for aqueous Knoevenagel condensation reactions."],"pmcid":["PMC11409447"],"pubmed_authors":["Bacchus A","Soliman AIA","Zare R","Fatehi P","Sutradhar S"],"additional_accession":[]},"is_claimable":false,"name":"Cationic lignin as an efficient and sustainable homogenous catalyst for aqueous Knoevenagel condensation reactions.","description":"Knoevenagel condensation is a chemical reaction between aldehydes and active methylene-containing compounds in the presence of heterogeneous, basic homogenous organic or inorganic catalysts and solvent or neat systems. Herein, we introduced a new strategy for this synthesis by using the aqueous solution of cationic kraft lignin (CKL) as a catalyst. The CKL was synthesized through the reaction of kraft lignin (KL) with glycidyltrimethylammonium chloride (GTMAC) in a basic medium. The optimal reaction conditions for the Knoevenagel reaction were 5% catalyst load (weight of catalyst to the weight of benzaldehyde), water as the solvent, and at room temperature, which generated the products with a yield of 97%, illustrating that the CKL was an effective homogenous and green catalyst. The result","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Sep","modification":"2025-04-06T12:52:18.792Z","creation":"2025-04-06T12:52:18.792Z"},"accession":"S-EPMC11409447","cross_references":{"pubmed":["39297031"],"doi":["10.1039/d4ra05763e"]}}