biostudies-literatureChoi ENCI NIH HHSNational Institutes of HealthNIH HHSpkae072https://www.ebi.ac.uk/biostudies/studies/S-EPMC11410193biostudies-literatureUnknown8(5)<h4>Background</h4>Recent therapeutic advances have improved survival among lung cancer (LC) patients, who are now at high risk of second primary lung cancer (SPLC). Hispanics comprise the largest minority in the United States, who have shown a lower LC incidence and mortality than other races, and yet their SPLC risk is poorly understood. We quantified the SPLC incidence patterns among Hispanics vs other races.<h4>Methods</h4>We used data from the Multiethnic Cohort, a population-based cohort of 5 races (African American, Japanese American, Hispanic, Native Hawaiian, and White), recruited between 1993 and 1996 and followed through 2017. We identified patients diagnosed with initial primary lung cancer (IPLC) and SPLC via linkage to Surveillance, Epidemiology, and End Results registries. WJNCI cancer spectrumRacial and ethnic differences in second primary lung cancer risk among lung cancer survivors.PMC11410193R37 CA2260811R01CA282793R01 CA282793Hua YLiang SYNeal JWChoi EHaiman CLeung ANBackhus LMHan SSWakelee HALe Marchand LWu JTSu CCCheng IfalseRacial and ethnic differences in second primary lung cancer risk among lung cancer survivors.<h4>Background</h4>Recent therapeutic advances have improved survival among lung cancer (LC) patients, who are now at high risk of second primary lung cancer (SPLC). Hispanics comprise the largest minority in the United States, who have shown a lower LC incidence and mortality than other races, and yet their SPLC risk is poorly understood. We quantified the SPLC incidence patterns among Hispanics vs other races.<h4>Methods</h4>We used data from the Multiethnic Cohort, a population-based cohort of 5 races (African American, Japanese American, Hispanic, Native Hawaiian, and White), recruited between 1993 and 1996 and followed through 2017. We identified patients diagnosed with initial primary lung cancer (IPLC) and SPLC via linkage to Surveillance, Epidemiology, and End Results registries. W2024-01-01T00:00:00Z2024 Sep2026-03-17T16:14:01.453Z2025-04-04T01:54:31.693ZS-EPMC114101933918600910.1093/jncics/pkae072