{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["15"],"submitter":["Clement G"],"pubmed_abstract":["Introduction
Bed rest can be used as a ground-based analog of the body unloading associated with spaceflight. In this study, we determined how strict head-down tilt bed rest affects subjects' performance of functional tests (sit-to-stand, tandem walk, walk-and-turn, dynamic posturography) that challenge astronauts' balance control systems immediately after they return from space.Methods
Forty-seven participants were assessed before and a few hours after 30 days of 6° head down tilt bed rest at the DLR:envihab facility. During this bed rest study, called SANS-CM, the participants were divided into 4 groups that either a) were positioned in head-down tilt continuously throughout the 30 days; b) sat upright for 6 h a day; c) were exposed to lower body negative pressure (LBNP) "],"journal":["Frontiers in physiology"],"pagination":["1442239"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11412840"],"repository":["biostudies-literature"],"pubmed_title":["Effects of intermittent seating upright, lower body negative pressure, and exercise on functional tasks performance after head-down tilt bed rest."],"pmcid":["PMC11412840"],"pubmed_authors":["Clement G","Macaulay TR","Moudy SC","Wood SJ","Mulder E"],"additional_accession":[]},"is_claimable":false,"name":"Effects of intermittent seating upright, lower body negative pressure, and exercise on functional tasks performance after head-down tilt bed rest.","description":"Introduction
Bed rest can be used as a ground-based analog of the body unloading associated with spaceflight. In this study, we determined how strict head-down tilt bed rest affects subjects' performance of functional tests (sit-to-stand, tandem walk, walk-and-turn, dynamic posturography) that challenge astronauts' balance control systems immediately after they return from space.Methods
Forty-seven participants were assessed before and a few hours after 30 days of 6° head down tilt bed rest at the DLR:envihab facility. During this bed rest study, called SANS-CM, the participants were divided into 4 groups that either a) were positioned in head-down tilt continuously throughout the 30 days; b) sat upright for 6 h a day; c) were exposed to lower body negative pressure (LBNP) ","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024","modification":"2026-06-04T03:08:46.933Z","creation":"2025-04-06T03:48:04.159Z"},"accession":"S-EPMC11412840","cross_references":{"pubmed":["39308978"],"doi":["10.3389/fphys.2024.1442239"]}}