{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Norkær E"],"funding":["Independent Research Fund Denmark","Danmarks Frie Forskningsfond","Medical Research Council","UK Research and Innovation Medical Research Council"],"pagination":["103-111"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11413477"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["179"],"pubmed_abstract":["Anomia is a common consequence following brain damage and a central symptom in semantic dementia (SD) and post-stroke aphasia (PSA), for instance. Picture naming tests are often used in clinical assessments and experience suggests that items vary systematically in their difficulty. Despite clinical intuitions and theoretical accounts, however, the existence and determinants of such a naming difficulty gradient remain to be empirically established and evaluated. Seizing the unique opportunity of two large-scale datasets of semantic dementia and post-stroke aphasia patients assessed with the same picture naming test, we applied an Item Response Theory (IRT) approach and we (a) established that an item naming difficulty gradient exists, which (b) partly differs between patient groups, and is "],"journal":["Cortex; a journal devoted to the study of the nervous system and behavior"],"pubmed_title":["Establishing and evaluating the gradient of item naming difficulty in post-stroke aphasia and semantic dementia."],"pmcid":["PMC11413477"],"funding_grant_id":["MR/R023883/1","DFF-1024-00139B","MC_UU_00005/18","MR/V031481/1"],"pubmed_authors":["Lambon Ralph MA","Halai AD","Woollams A","Norkær E","Schumacher R"],"additional_accession":[]},"is_claimable":false,"name":"Establishing and evaluating the gradient of item naming difficulty in post-stroke aphasia and semantic dementia.","description":"Anomia is a common consequence following brain damage and a central symptom in semantic dementia (SD) and post-stroke aphasia (PSA), for instance. Picture naming tests are often used in clinical assessments and experience suggests that items vary systematically in their difficulty. Despite clinical intuitions and theoretical accounts, however, the existence and determinants of such a naming difficulty gradient remain to be empirically established and evaluated. Seizing the unique opportunity of two large-scale datasets of semantic dementia and post-stroke aphasia patients assessed with the same picture naming test, we applied an Item Response Theory (IRT) approach and we (a) established that an item naming difficulty gradient exists, which (b) partly differs between patient groups, and is ","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Oct","modification":"2026-06-06T21:32:15.617Z","creation":"2025-04-04T00:51:43.918Z"},"accession":"S-EPMC11413477","cross_references":{"pubmed":["39167916"],"doi":["10.1016/j.cortex.2024.07.007"]}}