biostudies-literatureUnknown10(17)Huang L<h4>Background</h4>The unpleasant taste of polyethylene glycol (PEG) has been a hindrance to patients undergoing colonoscopy.<h4>Aim</h4>This study aims to determine whether the addition of a vitamin drink (Mizone) to the 4L split-dose PEG regimen would be effective in improving the solution's palatability, and reducing patient discomfort during bowel preparation.<h4>Methods</h4>The present prospective, single endoscopist-blinded, randomized controlled study randomly assigned patients into two groups: PEG + Mizone group (3.6 L of PEG solution plus 0.4 L of Mizone) and PEG group (4 L of PEG solution). Palatability was assessed using a Likert scale of 1-5. The adverse events, amount of unconsumed solution, and willingness to repeat the same process were recorded through a questionnaire. The Heliyone37590https://www.ebi.ac.uk/biostudies/studies/S-EPMC11413698biostudies-literatureVitamin drinks improve palatability and reduce adverse events associated to polyethylene glycol electrolyte solutions.PMC11413698Li CHuang LMa KWang XJiang YZfalseVitamin drinks improve palatability and reduce adverse events associated to polyethylene glycol electrolyte solutions.<h4>Background</h4>The unpleasant taste of polyethylene glycol (PEG) has been a hindrance to patients undergoing colonoscopy.<h4>Aim</h4>This study aims to determine whether the addition of a vitamin drink (Mizone) to the 4L split-dose PEG regimen would be effective in improving the solution's palatability, and reducing patient discomfort during bowel preparation.<h4>Methods</h4>The present prospective, single endoscopist-blinded, randomized controlled study randomly assigned patients into two groups: PEG + Mizone group (3.6 L of PEG solution plus 0.4 L of Mizone) and PEG group (4 L of PEG solution). Palatability was assessed using a Likert scale of 1-5. The adverse events, amount of unconsumed solution, and willingness to repeat the same process were recorded through a questionnaire. The 2024-01-01T00:00:00Z2024 Sep2026-06-04T09:44:05.757Z2025-04-04T01:54:36.007ZS-EPMC114136983930926810.1016/j.heliyon.2024.e37590