biostudies-literatureUnknown49Gunster JLB<h4>Purpose</h4>The aim of this study is to evaluate the cosmetic outcome among early stage breast cancer patients who underwent accelerated partial breast irradiation with either intraoperative electron radiotherapy (IOERT) or photon external beam radiotherapy (EB-APBI).<h4>Materials and methods</h4>This prospective multicenter cohort study enrolled women aged 60 years and older who underwent breast-conserving therapy. Following breast-conserving surgery, patients were treated with either IOERT or EB-APBI. Cosmetic outcome was evaluated over a 5 year follow-up period using both subjective scoring by patients and physicians, as well as objective scoring using BCCT.core software. Differences between treatments over time were described with mixed model analyses.<h4>Results</h4>A total of 241Clinical and translational radiation oncology100844https://www.ebi.ac.uk/biostudies/studies/S-EPMC11416622biostudies-literatureCosmetic outcome in patients with early stage breast cancer after accelerated partial breast irradiation using intraoperative or external beam radiotherapy.PMC11416622Petoukhova ALGunster JLBFisscher UJJacobs DHMStraver MScholten ANSpeijer GVerbeek-de Kanter AMerkus JMarijnen CAMMast MEfalseCosmetic outcome in patients with early stage breast cancer after accelerated partial breast irradiation using intraoperative or external beam radiotherapy.<h4>Purpose</h4>The aim of this study is to evaluate the cosmetic outcome among early stage breast cancer patients who underwent accelerated partial breast irradiation with either intraoperative electron radiotherapy (IOERT) or photon external beam radiotherapy (EB-APBI).<h4>Materials and methods</h4>This prospective multicenter cohort study enrolled women aged 60 years and older who underwent breast-conserving therapy. Following breast-conserving surgery, patients were treated with either IOERT or EB-APBI. Cosmetic outcome was evaluated over a 5 year follow-up period using both subjective scoring by patients and physicians, as well as objective scoring using BCCT.core software. Differences between treatments over time were described with mixed model analyses.<h4>Results</h4>A total of 2412024-01-01T00:00:00Z2024 Nov2026-06-04T07:51:08.675Z2025-04-03T23:48:54.625ZS-EPMC114166223930863210.1016/j.ctro.2024.100844