{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8(9)"],"submitter":["Sparacio A"],"pubmed_abstract":["Mindfulness witnessed a substantial popularity surge in the past decade, especially as digitally self-administered interventions became available at relatively low costs. Yet, it is uncertain whether they effectively help reduce stress. In a preregistered (OSF https://doi.org/10.17605/OSF.IO/UF4JZ ; retrospective registration at ClinicalTrials.gov NCT06308744 ) multi-site study (n<sub>sites</sub> = 37, n<sub>participants</sub> = 2,239, 70.4% women, M<sub>age</sub> = 22.4, s.d.<sub>age</sub> = 10.1, all fluent English speakers), we experimentally tested whether four single, standalone mindfulness exercises effectively reduced stress, using Bayesian mixed-effects models. All exercises proved to be more efficacious than the active control. We observed a mean difference of 0.27 (d = -0.56; 95% confidence interval, -0.43 to -0.69) between the control condition (M = 1.95, s.d. = 0.50) and the condition with the largest stress reduction (body scan: M = 1.68, s.d. = 0.46). Our findings suggest that mindfulness may be beneficial for reducing self-reported short-term stress for English speakers from higher-income countries."],"journal":["Nature human behaviour"],"pagination":["1716-1725"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11420060"],"repository":["biostudies-literature"],"pubmed_title":["Self-administered mindfulness interventions reduce stress in a large, randomized controlled multi-site study."],"pmcid":["PMC11420060"],"pubmed_authors":["Griffin SM","DeSousa M","Ross RM","Schmidt K","Derrick JL","McDonald JS","Segundo J","Fransham C","Dickerson SS","Sparacio A","Dunne S","Burgess H","LaBoucane A","Jaklin V","Meese WB","Watermeyer TJ","Spiessens C","Ford MB","Howell JL","Jiga-Boy GM","Hawk CE","Ribeiro G","Goldsmith CM","van der Schans KL","Ng Tseung-Wong C","Landvatter J","Baranski MF","Pescatore S","Brenton S","Ropovik I","Standiford Reyes L","IJzerman H","Benson JM","Wong CC","Tacana T","Linden AH","Benz ABE","Ma-Kellams C","Wunder ZI","Pierce JD","Nylin CE","Davis WE","Fuglestad PT","Kovas Y","Ziebell P","O'Brien LV","Day MV","Francis Z","Higgins WC","Diller SJ","Allahghadri M","Jewell CL","Brooks JC","Stanley SK","Strickland MG","Urgyen T","Kubler A","Skakoon-Sparling S","Blocker H","Stone BM","Giorgini F","Uchino BN"],"additional_accession":[]},"is_claimable":false,"name":"Self-administered mindfulness interventions reduce stress in a large, randomized controlled multi-site study.","description":"Mindfulness witnessed a substantial popularity surge in the past decade, especially as digitally self-administered interventions became available at relatively low costs. Yet, it is uncertain whether they effectively help reduce stress. In a preregistered (OSF https://doi.org/10.17605/OSF.IO/UF4JZ ; retrospective registration at ClinicalTrials.gov NCT06308744 ) multi-site study (n<sub>sites</sub> = 37, n<sub>participants</sub> = 2,239, 70.4% women, M<sub>age</sub> = 22.4, s.d.<sub>age</sub> = 10.1, all fluent English speakers), we experimentally tested whether four single, standalone mindfulness exercises effectively reduced stress, using Bayesian mixed-effects models. All exercises proved to be more efficacious than the active control. We observed a mean difference of 0.27 (d = -0.56; 95% confidence interval, -0.43 to -0.69) between the control condition (M = 1.95, s.d. = 0.50) and the condition with the largest stress reduction (body scan: M = 1.68, s.d. = 0.46). Our findings suggest that mindfulness may be beneficial for reducing self-reported short-term stress for English speakers from higher-income countries.","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Sep","modification":"2026-04-29T23:18:29.767Z","creation":"2025-04-04T19:38:51.622Z"},"accession":"S-EPMC11420060","cross_references":{"pubmed":["38862815"],"doi":["10.1038/s41562-024-01907-7"]}}