{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12"],"submitter":["Dieter V"],"pubmed_abstract":["<h4>Background</h4>Exercise therapy is recommended by international guidelines as a core treatment for patients with knee osteoarthritis. However, there is a significant gap between recommendations and practice in health care. Digital exercise apps are promising to help solve this undersupply.<h4>Objective</h4>This study aims to evaluate the efficacy of a 12-week fully automated app-based exercise intervention with and without a supporting knee brace on health-related outcomes, performance measures, and adherence in patients with knee osteoarthritis.<h4>Methods</h4>This closed user group trial included participants with moderate to severe unicondylar painful knee osteoarthritis. Randomization was 1:1:2 into an intervention group (IG) with 2 subgroups (app-based training [IG A] and app-base"],"journal":["JMIR mHealth and uHealth"],"pagination":["e54356"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11420596"],"repository":["biostudies-literature"],"pubmed_title":["Efficacy of the mHealth-Based Exercise Intervention re.flex for Patients With Knee Osteoarthritis: Pilot Randomized Controlled Trial."],"pmcid":["PMC11420596"],"pubmed_authors":["Janssen P","Dieter V","Krauss I"],"additional_accession":[]},"is_claimable":false,"name":"Efficacy of the mHealth-Based Exercise Intervention re.flex for Patients With Knee Osteoarthritis: Pilot Randomized Controlled Trial.","description":"<h4>Background</h4>Exercise therapy is recommended by international guidelines as a core treatment for patients with knee osteoarthritis. However, there is a significant gap between recommendations and practice in health care. Digital exercise apps are promising to help solve this undersupply.<h4>Objective</h4>This study aims to evaluate the efficacy of a 12-week fully automated app-based exercise intervention with and without a supporting knee brace on health-related outcomes, performance measures, and adherence in patients with knee osteoarthritis.<h4>Methods</h4>This closed user group trial included participants with moderate to severe unicondylar painful knee osteoarthritis. Randomization was 1:1:2 into an intervention group (IG) with 2 subgroups (app-based training [IG A] and app-base","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Sep","modification":"2026-06-04T12:17:16.916Z","creation":"2025-04-03T23:48:24.611Z"},"accession":"S-EPMC11420596","cross_references":{"pubmed":["39250181"],"doi":["10.2196/54356"]}}