{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kiakuvue YN"],"funding":["Bill &amp; Melinda Gates Foundation"],"pagination":["e0310528"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11423971"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["19(9)"],"pubmed_abstract":["<h4>Introduction</h4>Bacterial meningitis is a major cause of death, with an approximate case fatality rate of 37% across all age groups in South Africa. This study aimed to describe the demographic and pathogen characteristics of incident meningitis in children aged <1 year in South Africa from 2014 through 2018, during a period when Haemophilus influenzae type b vaccine and pneumococcal conjugate vaccines (PCV) were both included in the expanded program on immunization (EPI).<h4>Methods</h4>We conducted a cohort study of routine laboratory data in the National Health Laboratory Service Corporate Data Warehouse, which covers approximately 80% of the South African population. We defined a case of laboratory-confirmed bacterial meningitis as any person aged <1 year with meningitis diagnosed"],"journal":["PloS one"],"pubmed_title":["Demographic and pathogen characteristics of incident bacterial meningitis in infants in South Africa: A cohort study."],"pmcid":["PMC11423971"],"funding_grant_id":["OPP1208882"],"pubmed_authors":["Kiakuvue YN","Mashau R","Gottberg AV","Govender N","Mall S","Meiring S","Cohen C"],"additional_accession":[]},"is_claimable":false,"name":"Demographic and pathogen characteristics of incident bacterial meningitis in infants in South Africa: A cohort study.","description":"<h4>Introduction</h4>Bacterial meningitis is a major cause of death, with an approximate case fatality rate of 37% across all age groups in South Africa. This study aimed to describe the demographic and pathogen characteristics of incident meningitis in children aged <1 year in South Africa from 2014 through 2018, during a period when Haemophilus influenzae type b vaccine and pneumococcal conjugate vaccines (PCV) were both included in the expanded program on immunization (EPI).<h4>Methods</h4>We conducted a cohort study of routine laboratory data in the National Health Laboratory Service Corporate Data Warehouse, which covers approximately 80% of the South African population. We defined a case of laboratory-confirmed bacterial meningitis as any person aged <1 year with meningitis diagnosed","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024","modification":"2026-06-05T05:05:03.959Z","creation":"2025-04-07T07:29:12.695Z"},"accession":"S-EPMC11423971","cross_references":{"pubmed":["39321191"],"doi":["10.1371/journal.pone.0310528"]}}