{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bontempi B"],"funding":["CNRS","ANR","France Telecom R&D","University of Bordeaux","COMOBIO project carried out within the RTRN research program (National Network for Research in Telecommunication)"],"pagination":["1954"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11428239"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(9)"],"pubmed_abstract":["Over the last two decades, animal models have been used to evaluate the physiological and cognitive effects of mobile phone exposure. Here, we used a head-only exposure system in rats to determine whether exposure to 900 MHz GSM electromagnetic fields (EMFs) induces regional changes in neuronal activation as revealed by c-Fos imaging. In a first study, rats were exposed for 2 h to brain average specific absorption rates (BASARs) ranging from 0.5 to 6 W/kg. Changes in neuronal activation were found to be dose-dependent, with significant increases in c-Fos expression occurring at BASAR of 1 W/kg in prelimbic, infralimbic, frontal, and cingulate cortices. In a second study, rats were submitted to either a spatial working memory (WM) task in a radial maze or a spatial reference memory (RM) tas"],"journal":["Biomedicines"],"pubmed_title":["Effects of Head-Only Exposure to 900 MHz GSM Electromagnetic Fields in Rats: Changes in Neuronal Activity as Revealed by c-Fos Imaging without Concomitant Cognitive Impairments."],"pmcid":["PMC11428239"],"funding_grant_id":["#ANR-10-CESA-002"],"pubmed_authors":["Jay TM","Dubreuil D","Leveque P","Bontempi B","Edeline JM"],"additional_accession":[]},"is_claimable":false,"name":"Effects of Head-Only Exposure to 900 MHz GSM Electromagnetic Fields in Rats: Changes in Neuronal Activity as Revealed by c-Fos Imaging without Concomitant Cognitive Impairments.","description":"Over the last two decades, animal models have been used to evaluate the physiological and cognitive effects of mobile phone exposure. Here, we used a head-only exposure system in rats to determine whether exposure to 900 MHz GSM electromagnetic fields (EMFs) induces regional changes in neuronal activation as revealed by c-Fos imaging. In a first study, rats were exposed for 2 h to brain average specific absorption rates (BASARs) ranging from 0.5 to 6 W/kg. Changes in neuronal activation were found to be dose-dependent, with significant increases in c-Fos expression occurring at BASAR of 1 W/kg in prelimbic, infralimbic, frontal, and cingulate cortices. In a second study, rats were submitted to either a spatial working memory (WM) task in a radial maze or a spatial reference memory (RM) tas","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Aug","modification":"2026-05-14T03:21:52.317Z","creation":"2025-04-05T08:58:48.267Z"},"accession":"S-EPMC11428239","cross_references":{"pubmed":["39335468"],"doi":["10.3390/biomedicines12091954"]}}