biostudies-literatureUnknown28(1)Reizine F<h4>Background</h4>While SARS-CoV2 infection has been shown to be a significant risk-factor for several secondary bacterial, viral and Aspergillus infections, its impact on intensive care unit (ICU)-acquired candidemia (ICAC) remains poorly explored.<h4>Method</h4>Using the REA-REZO network (French surveillance network of ICU-acquired infections), we included all adult patients hospitalized for a medical reason of admission in participating ICUs for at least 48 h from January 2020 to January 2023. To account for confounders, a non-parsimonious propensity score matching was performed. Rates of ICAC according to SARS-CoV2 status were compared in matched patients. Factors associated with ICAC in COVID-19 patients were also assessed using a Fine-Gray model.<h4>Results</h4>A total of 55,268 patCritical care (London, England)320https://www.ebi.ac.uk/biostudies/studies/S-EPMC11429030biostudies-literatureRelationship between SARS-CoV-2 infection and ICU-acquired candidemia in critically ill medical patients: a multicenter prospective cohort study.PMC11429030Comparot SPoiron LFatah ARemy ECourouble PEldin CMeyer EPFriggeri AChassaing GDelhomme JDurand MLeon RPavillard FBeilouny BBelin NRoustan JPicault SJulien GBele NCorno GPatrigeon RGDeffarges DLouart BBouhara ALedochowski SEgreteau PYLecoutre LHayo FAurel CDelanghe FPibre JBernerd CBarjon GMariot JPascal MYassine HMaxime VTranvan DHenry CBeague SPradel GChauvet MDjedaini KMartres PQuenee VAlfandari SLe QVVallet CManzon CRobine APrelipcean CNacim ABirot Jaulin FCastelain VRimmele TCanu NVasse LBonjean SGleize MFedun YCohen AFarfour EGeorges HTasle MTrivier DMallaret MRLamant KHerbland APerdrix CBulyez SLafon BLe Fall FRicome SMeunier OLaunoy ACatanese VLevrard MAudibert GDupont LPillot JVitris MBaune PRolland-Jacob GZanre LFlorentin AMeziani FTroche GNizou JYCorne PMaheu CRohr LRougier CGasan GBoutreux SLabruyere MArgaus LMuller CLaurent BLarroude PPina PGalland CLavigne TSechaud DLe Tallec BLacroix SSirodot MDuhoo SGrisi BGibot SPommier CDerramond FDelorme MDulac TThiolliere FDananche CBianchi CLe Floch ASAlvarez AJean ALignereux AThiphagne BMartin ASaliba FBajolet OVenelle MDijols IRoche ACCortes EDiaw FClayer CDurand Joly IDabbachi MSimac CGroleau CSi-Ali AThomas-Hervieu AValdeyron MLBouillard PZylberfajn CDelias JPVacheron CHRichard JCChopin FJoron SStoeckel VHyvernat HMartin EMardrus PTonnelier AMoschietto SDassant DEspinasse FMartin MBerrouane YMassart NLe Coq MHuntzinger JVenot CSaint-Leger MBarbut FGoret MUrsulet LHammad ELier MLLa Combe BSavey AChartier VDelastre ODupin CMachut ABordes-Couecou STagawa PKempf JREAREZO study groupHaond CPicos Gil SFribourg ABourigault CLepouse CBouzidi HDopeux LJolibois BChausset RFerreira LBourzeix SGaubert-Duclos JFleurial VGlanard ALepape ARoques AGiacardi CSimon GVincent JFAllaire AGrau DVan Rossem VCapron MMaindron ALescot TToro APeghaire SCallanquin MGallais-Hoff SReynaud Deforges SReizine FMankikian BMunier-Marion EPetit JSFinge TNeulier CDaurat AGeneau IChubilleau CGeffriaud TPalitta CBertrand JGerbier Colomban SBrochart JTrusson RGalliot RDaumas MGauzere VGuignabert CCattaneo IPugliesi PSHausermann MHPlattier RDusseau JYCarbognani DDaroukh AVieillard-Baron ABiangoma SRaposo OTinturier FKnani LMallard FNicolas FFillatre PLawrence CCrombe CPicard WPassouant OBerrouba AGrolier-Bois LGarnier SMansour ACornesse MEGourgues MCurnier VHadj-Slimane FfalseRelationship between SARS-CoV-2 infection and ICU-acquired candidemia in critically ill medical patients: a multicenter prospective cohort study.<h4>Background</h4>While SARS-CoV2 infection has been shown to be a significant risk-factor for several secondary bacterial, viral and Aspergillus infections, its impact on intensive care unit (ICU)-acquired candidemia (ICAC) remains poorly explored.<h4>Method</h4>Using the REA-REZO network (French surveillance network of ICU-acquired infections), we included all adult patients hospitalized for a medical reason of admission in participating ICUs for at least 48 h from January 2020 to January 2023. To account for confounders, a non-parsimonious propensity score matching was performed. Rates of ICAC according to SARS-CoV2 status were compared in matched patients. Factors associated with ICAC in COVID-19 patients were also assessed using a Fine-Gray model.<h4>Results</h4>A total of 55,268 pat2024-01-01T00:00:00Z2024 Sep2026-06-14T04:59:41.215Z2025-04-07T02:50:20.253ZS-EPMC114290303933425410.1186/s13054-024-05104-w