{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16(18)"],"submitter":["Yamada N"],"pubmed_abstract":["We investigated the effects of <i>Lactobacillus paragasseri</i> OLL2716 on gastrointestinal symptoms in healthy adults with gastric complaints. In this randomized, double-blind, placebo-controlled trial, 174 healthy Japanese adults were randomly assigned to an OLL2716 or placebo group, and each group consumed 85 g of yogurt containing <i>L. paragasseri</i> OLL2716 or placebo yogurt daily for 12 weeks. The primary endpoint was the change in gastric symptoms from baseline as per the participants' questionnaires at 6 and 12 weeks. The secondary endpoints were changes from baseline in the short-form Nepean Dyspepsia Index (SF-NDI), the Gastrointestinal Symptom Rating Scale (GSRS), and the Council on Nutrition Appetite Questionnaire-Japanese (CNAQ-J) scores at 6 and 12 weeks. The primary endpoi"],"journal":["Nutrients"],"pagination":["3188"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11434869"],"repository":["biostudies-literature"],"pubmed_title":["The Beneficial Effects of Regular Intake of &lt;i&gt;Lactobacillus paragasseri&lt;/i&gt; OLL2716 on Gastric Discomfort in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study."],"pmcid":["PMC11434869"],"pubmed_authors":["Toshimitsu T","Sato A","Kano H","Yamada N","Nagira A","Hojo K","Kobayashi K"],"additional_accession":[]},"is_claimable":false,"name":"The Beneficial Effects of Regular Intake of &lt;i&gt;Lactobacillus paragasseri&lt;/i&gt; OLL2716 on Gastric Discomfort in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study.","description":"We investigated the effects of <i>Lactobacillus paragasseri</i> OLL2716 on gastrointestinal symptoms in healthy adults with gastric complaints. In this randomized, double-blind, placebo-controlled trial, 174 healthy Japanese adults were randomly assigned to an OLL2716 or placebo group, and each group consumed 85 g of yogurt containing <i>L. paragasseri</i> OLL2716 or placebo yogurt daily for 12 weeks. The primary endpoint was the change in gastric symptoms from baseline as per the participants' questionnaires at 6 and 12 weeks. The secondary endpoints were changes from baseline in the short-form Nepean Dyspepsia Index (SF-NDI), the Gastrointestinal Symptom Rating Scale (GSRS), and the Council on Nutrition Appetite Questionnaire-Japanese (CNAQ-J) scores at 6 and 12 weeks. The primary endpoi","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Sep","modification":"2025-04-18T19:44:50.748Z","creation":"2025-04-07T07:32:04.367Z"},"accession":"S-EPMC11434869","cross_references":{"pubmed":["39339788"],"doi":["10.3390/nu16183188"]}}