biostudies-literatureUnknown16(18)Yamada NWe investigated the effects of <i>Lactobacillus paragasseri</i> OLL2716 on gastrointestinal symptoms in healthy adults with gastric complaints. In this randomized, double-blind, placebo-controlled trial, 174 healthy Japanese adults were randomly assigned to an OLL2716 or placebo group, and each group consumed 85 g of yogurt containing <i>L. paragasseri</i> OLL2716 or placebo yogurt daily for 12 weeks. The primary endpoint was the change in gastric symptoms from baseline as per the participants' questionnaires at 6 and 12 weeks. The secondary endpoints were changes from baseline in the short-form Nepean Dyspepsia Index (SF-NDI), the Gastrointestinal Symptom Rating Scale (GSRS), and the Council on Nutrition Appetite Questionnaire-Japanese (CNAQ-J) scores at 6 and 12 weeks. The primary endpoiNutrients3188https://www.ebi.ac.uk/biostudies/studies/S-EPMC11434869biostudies-literatureThe Beneficial Effects of Regular Intake of &lt;i&gt;Lactobacillus paragasseri&lt;/i&gt; OLL2716 on Gastric Discomfort in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study.PMC11434869Toshimitsu TSato AKano HYamada NNagira AHojo KKobayashi KfalseThe Beneficial Effects of Regular Intake of &lt;i&gt;Lactobacillus paragasseri&lt;/i&gt; OLL2716 on Gastric Discomfort in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study.We investigated the effects of <i>Lactobacillus paragasseri</i> OLL2716 on gastrointestinal symptoms in healthy adults with gastric complaints. In this randomized, double-blind, placebo-controlled trial, 174 healthy Japanese adults were randomly assigned to an OLL2716 or placebo group, and each group consumed 85 g of yogurt containing <i>L. paragasseri</i> OLL2716 or placebo yogurt daily for 12 weeks. The primary endpoint was the change in gastric symptoms from baseline as per the participants' questionnaires at 6 and 12 weeks. The secondary endpoints were changes from baseline in the short-form Nepean Dyspepsia Index (SF-NDI), the Gastrointestinal Symptom Rating Scale (GSRS), and the Council on Nutrition Appetite Questionnaire-Japanese (CNAQ-J) scores at 6 and 12 weeks. The primary endpoi2024-01-01T00:00:00Z2024 Sep2025-04-18T19:44:50.748Z2025-04-07T07:32:04.367ZS-EPMC114348693933978810.3390/nu16183188