biostudies-literatureTaheri DIran National Science Foundation22403https://www.ebi.ac.uk/biostudies/studies/S-EPMC11436623biostudies-literatureUnknown14(1)Besides many efforts on the detection and quantification of reactive oxygen and nitrogen species (RONSs) in the aqueous media activated by the cold atmospheric plasma, to get a better insight into the dominant mechanism and reactive species in medical applications, a challenge still remains in monitoring the real-time evaluation of them. To this end, in the present work, relying on the photonic technology based on the time-resolved phosphorescence spectroscopy, real-time tracking of RONSs concentration in treated aqueous media is achieved by following the dissolved oxygen (DO) production/consumption. Using a photonic-based dissolved oxygen sensor, the dependence of real-time RONS concentration evaluation of plasma activated medium on plasma nozzle distance, non-thermal plasma jet exposure Scientific reportsRealtime RONS monitoring of cold plasma-activated aqueous media based on time-resolved phosphorescence spectroscopy.PMC114366234020795MirzaHosseini FKMehdian HRobert EHajisharifi KHeydari ETaheri DfalseRealtime RONS monitoring of cold plasma-activated aqueous media based on time-resolved phosphorescence spectroscopy.Besides many efforts on the detection and quantification of reactive oxygen and nitrogen species (RONSs) in the aqueous media activated by the cold atmospheric plasma, to get a better insight into the dominant mechanism and reactive species in medical applications, a challenge still remains in monitoring the real-time evaluation of them. To this end, in the present work, relying on the photonic technology based on the time-resolved phosphorescence spectroscopy, real-time tracking of RONSs concentration in treated aqueous media is achieved by following the dissolved oxygen (DO) production/consumption. Using a photonic-based dissolved oxygen sensor, the dependence of real-time RONS concentration evaluation of plasma activated medium on plasma nozzle distance, non-thermal plasma jet exposure 2024-01-01T00:00:00Z2024 Sep2025-04-04T02:04:57.935Z2025-04-04T02:04:57.935ZS-EPMC114366233933374310.1038/s41598-024-73585-4