biostudies-literatureYin XNational Natural Science Foundation of ChinaNational Natural Science Foundation of China (National Science Foundation of China)8409https://www.ebi.ac.uk/biostudies/studies/S-EPMC11436733biostudies-literatureUnknown15(1)The olfactory system can generate unique sensory memories of various odorous molecules, guiding emotional and cognitive decisions. However, most existing electronic noses remain constrained to momentary concentration, failing to trigger specific memories for different smells. Here, we report an artificial olfactory memory system utilizing conductive metal-organic frameworks (Ce-HHTP) that integrates sensing and memory and exhibits short- and long-term memory responses to alcohols and aldehydes. Experiments and theoretical calculations show that distinct memories are derived from the specific combinations of Ce-HHTP with O atoms in different guest. An unmanned aircraft equipped with this system realized the sensory memories in established areas. Moreover, the fusion of portable detection boNature communicationsArtificial olfactory memory system based on conductive metal-organic frameworks.PMC11436733201874005219254052210414122004122Yin XTang ZQiao XLi CZhang KZhang HWang TChen XXue ZZhou XYe HfalseArtificial olfactory memory system based on conductive metal-organic frameworks.The olfactory system can generate unique sensory memories of various odorous molecules, guiding emotional and cognitive decisions. However, most existing electronic noses remain constrained to momentary concentration, failing to trigger specific memories for different smells. Here, we report an artificial olfactory memory system utilizing conductive metal-organic frameworks (Ce-HHTP) that integrates sensing and memory and exhibits short- and long-term memory responses to alcohols and aldehydes. Experiments and theoretical calculations show that distinct memories are derived from the specific combinations of Ce-HHTP with O atoms in different guest. An unmanned aircraft equipped with this system realized the sensory memories in established areas. Moreover, the fusion of portable detection bo2024-01-01T00:00:00Z2024 Sep2025-04-03T23:48:19.15Z2025-04-03T23:48:19.15ZS-EPMC114367333933310110.1038/s41467-024-52567-0