biostudies-literatureWang YSHDCNKRDPCShanghai Municipal Hospital Development CenterBengbu Medical University Postgraduate Research and Innovation Programme ProjectNational Health Commission capacity building and continuing Education centerNational Natural Science Foundation of ChinaNational Key Research and Development Program of ChinaMilitary Commission health care special projectNNSFC913-923https://www.ebi.ac.uk/biostudies/studies/S-EPMC11444853biostudies-literatureUnknown25(10)<h4>Objective</h4>To prospectively compare single-shot (SS) echo-planar imaging (EPI) and field-of-view optimized and constrained undistorted single-shot multiplexed sensitivity-encoding (FOCUS MUSE) for diffusion-weighted imaging (DWI) in evaluating thyroid-associated ophthalmopathy (TAO).<h4>Materials and methods</h4>SS EPI and FOCUS MUSE DWIs were obtained from 39 patients with TAO (18 male; mean ± standard deviation: 48.3 ± 13.3 years) and 26 healthy controls (9 male; mean ± standard deviation: 43.0 ± 18.5 years). Two radiologists scored the visual image quality using a 4-point Likert scale. The image quality score, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and apparent diffusion coefficient (ADC) of extraocular muscles (EOMs) were compared between the two DWIs. DiffeKorean journal of radiologyProspective Comparison of FOCUS MUSE and Single-Shot Echo-Planar Imaging for Diffusion-Weighted Imaging in Evaluating Thyroid-Associated Ophthalmopathy.PMC114448532022YFC2410002SHDC22022310-BYXFSC2022JJSJ010Byycx2303622BJZ07822719942022YFC241000082170858Zhang TLi TCui YXiao YJiang QMa YNi SChen XWang YDai JCheng YfalseProspective Comparison of FOCUS MUSE and Single-Shot Echo-Planar Imaging for Diffusion-Weighted Imaging in Evaluating Thyroid-Associated Ophthalmopathy.<h4>Objective</h4>To prospectively compare single-shot (SS) echo-planar imaging (EPI) and field-of-view optimized and constrained undistorted single-shot multiplexed sensitivity-encoding (FOCUS MUSE) for diffusion-weighted imaging (DWI) in evaluating thyroid-associated ophthalmopathy (TAO).<h4>Materials and methods</h4>SS EPI and FOCUS MUSE DWIs were obtained from 39 patients with TAO (18 male; mean ± standard deviation: 48.3 ± 13.3 years) and 26 healthy controls (9 male; mean ± standard deviation: 43.0 ± 18.5 years). Two radiologists scored the visual image quality using a 4-point Likert scale. The image quality score, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and apparent diffusion coefficient (ADC) of extraocular muscles (EOMs) were compared between the two DWIs. Diffe2024-01-01T00:00:00Z2024 Oct2026-06-06T22:14:22.309Z2025-04-04T02:36:03.712ZS-EPMC114448533934454810.3348/kjr.2024.0177